ubiquitin specific peptidase 17-like 2

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Synonym

deubiquitinating enzyme 3, DUB3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.01 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0.01 pituitary:- thyroid/parathyroid:0 adrenal gland:0.00 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_201402
Gene ID 377630
Unigene ID Hs.531448
Probe set ID -
Ensembl ID ENSG00000223443
GTEx ID ENSG00000223443

Orthologous Gene

Mouse[7]  NM_007887, NM_001001559, NM_010089, NM_201409
Rat[7]  NM_007887, NM_001001559, NM_010089, NM_201409

Chromosomal Region

8p23.1  [11,994,677  -  11,996,586]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9806828
10936051
11941478
14699124
15780755
16611142
17109758
19188362
19615732
19718026
20147298
20228807
20228808
20368735
20388806
20403174
20715989
21239494
21448158
23773437
24704006

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007049  cell cycle
GO:0000075  cell cycle checkpoint
GO:0007093  mitotic cell cycle checkpoint
GO:0031064  negative regulation of histone deacetylation
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0034261  negative regulation of Ras GTPase activity
GO:0032321  positive regulation of Rho GTPase activity
GO:0016579  protein deubiquitination
GO:0071108  protein K48-linked deubiquitination
GO:0070536  protein K63-linked deubiquitination
GO:0042981  regulation of apoptosis
GO:0030334  regulation of cell migration
GO:0042127  regulation of cell proliferation
GO:0050691  regulation of defense response to virus by host
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity