ADP-ribosylation factor 4

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Synonym

ARF4, ADP-ribosylation factor 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.71 cerebellum:8.48 brain stem:8.74 corpus callosum/glia:8.66 pineal gland:- peripheral nerve:9.47 spine:9.17 retina:- eye:- artery/aorta:9.68 vein:9.78 lymphnode:9.11 peripheral blood:- spleen:8.91 thymus:8.96 bone marrow:8.93 adipose:9.69 bone:- skin:9.42
CAGE cerebrum:4.59 cerebellum:- brain stem:4.66 corpus callosum/glia:4.76 pineal gland:4.67 peripheral nerve:- spine:4.96 retina:- eye:- artery/aorta:5.73 vein:4.77 lymphnode:5.37 peripheral blood:- spleen:5.00 thymus:4.31 bone marrow:- adipose:5.49 bone:- skin:-
RNA-seq cerebrum:5.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.48 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.33 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:10.17 placenta:10.19 prostate:10.43 ovary:9.96 testis:9.79 heart:9.29 muscle:8.66 esophagus:9.52 stomach:9.97 intestine:9.76 colon:9.82 liver/hepato:9.23 lung:9.72 bladder:- kidney:9.39 pituitary:9.75 thyroid/parathyroid:9.82 adrenal gland:10.02 pancreas:9.97 breast:9.76 salivary:10.49
CAGE uterus:5.32 placenta:5.90 prostate:5.15 ovary:5.46 testis:5.44 heart:5.23 muscle:4.37 esophagus:5.27 stomach:- intestine:5.54 colon:5.14     liver/hepato:6.41    lung:5.61 bladder:5.35 kidney:5.40 pituitary:5.55 thyroid/parathyroid:5.43 adrenal gland:- pancreas:6.03 breast:5.55 salivary:6.16
RNA-seq uterus:- placenta:- prostate:6.43 ovary:7.07 testis:6.62 heart:5.04 muscle:4.50 esophagus:- stomach:- intestine:- colon:6.31     liver/hepato:6.72        lung:6.94    bladder:- kidney:6.65 pituitary:- thyroid/parathyroid:6.39 adrenal gland:5.87 pancreas:- breast:6.80 salivary:-

Gene Information

IDs

Refseq ID NM_001660
Gene ID 378
Unigene ID -
Probe set ID 201097_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000168374
GTEx ID ENSG00000168374

Orthologous Gene

Mouse[3]  NM_007479
Rat [0]  

Chromosomal Region

3p14.3  [57,557,090  -  57,583,947]

Gene Family (Interpro ID)

IPR006689  ARF/SAR superfamily
IPR013753  Ras
IPR001806  Ras GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR006687  Small GTPase SAR1-type

Link to Pubmed  (Pubmed ID)

1447192
1899243
2105501
2107548
7956370
8355790
8491770
9180902
10099884
10524252
10593962
10828067
11481332
12446727
12477932
15049518
15231747
15489334
16344560
17314511
18781797
19041174
19167051
19322201
19615732
19946888
20360068
20881058
21139048
21145461
21319273
21853274
21890473
21906983
21963094
21988832
22004728
22105072
22185782
22268729
22304920
22952844
23125841
23464991
23783033
24163370
24185178
24250222
24337577
24561123

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0006184  GTP catabolic process
GO:0015031  protein transport
GO:0048678  response to axon injury
GO:0007264  small GTPase mediated signal transduction
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0005794  Golgi apparatus
GO:0005886  plasma membrane

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005515  protein binding