acetyl-Coenzyme A acetyltransferase 1

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Synonym

ACAT1, Acetoacetyl-CoA thiolase, THIL, MAT, T2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:21.30

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:11.80

artery/aorta:-

vein:66.60

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:121

bone:12.80

skin:38.40

GeneChip

cerebrum:8.07

cerebellum:7.90

brain stem:8.23

corpus callosum/glia:8.21

pineal gland:-

peripheral nerve:8.62

spine:8.26

retina:-

eye:-

artery/aorta:8.52

vein:9.34

lymphnode:7.81

peripheral blood:-

spleen:7.67

thymus:6.94

bone marrow:7.87

adipose:9.29

bone:-

skin:8.49

CAGE

cerebrum:4.11

cerebellum:-

brain stem:4.16

corpus callosum/glia:4.10

pineal gland:4.21

peripheral nerve:-

spine:4.33

retina:-

eye:-

artery/aorta:4.38

vein:4.46

lymphnode:3.64

peripheral blood:-

spleen:3.97

thymus:2.42

bone marrow:-

adipose:4.78

bone:-

skin:-

RNA-seq

cerebrum:4.91

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.09

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.55

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:3.60

prostate:56.30

ovary:37.30

testis:30.30

heart:63.90

muscle:180.80

esophagus:342.80

stomach:-

intestine:-

colon:67.80

liver/hepato:21.10

lung:4.90

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:17.80

breast:74.30

salivary:-

GeneChip

uterus:8.46

placenta:6.97

prostate:8.31

ovary:8.61

testis:9.38

heart:10.04

muscle:10.95

esophagus:8.84

stomach:8.61

intestine:9.17

colon:8.38

liver/hepato:11.03

lung:8.38

bladder:-

kidney:11.24

pituitary:8.40

thyroid/parathyroid:8.75

adrenal gland:9.63

pancreas:9.64

breast:8.58

salivary:9.89

CAGE

uterus:4.18

placenta:3.14

prostate:4.03

ovary:4.24

testis:4.25

heart:5.36

muscle:5.95

esophagus:4.11

stomach:-

intestine:4.29

colon:4.69

liver/hepato:7.32

lung:4.17

bladder:4.45

kidney:5.95

pituitary:4.07

thyroid/parathyroid:3.97

adrenal gland:-

pancreas:5.11

breast:4.77

salivary:5.24

RNA-seq

uterus:-

placenta:-

prostate:5.24

ovary:5.25

testis:5.56

heart:6.88

muscle:6.47

esophagus:-

stomach:-

intestine:-

colon:5.18

liver/hepato:8.29

lung:4.28

bladder:-

kidney:6.85

pituitary:-

thyroid/parathyroid:6.10

adrenal gland:5.14

pancreas:-

breast:6.17

salivary:-

IDs

Refseq ID	NM_000019
Gene ID	38
Unigene ID	Hs.232375
Probe set ID	205412_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000075239
GTEx ID	ENSG00000075239

Orthologous Gene

Mouse[3]	NM_144784
Rat [0]

Chromosomal Region

11q22.3 [107,992,243 - 108,018,503]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002155

Thiolase

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0060612	adipose tissue development
GO:0007420	brain development
GO:0009083	branched chain family amino acid catabolic process
GO:0046950	cellular ketone body metabolic process
GO:0044255	cellular lipid metabolic process
GO:0034641	cellular nitrogen compound metabolic process
GO:0046951	ketone body biosynthetic process
GO:0046952	ketone body catabolic process
GO:0001889	liver development
GO:0051260	protein homooligomerization
GO:0009725	response to hormone stimulus
GO:0014070	response to organic cyclic substance
GO:0042594	response to starvation

Cellular Component

GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion

Molecular Function

GO:0003985	acetyl-CoA C-acetyltransferase activity
GO:0050662	coenzyme binding
GO:0019899	enzyme binding
GO:0046872	metal ion binding
GO:0042803	protein homodimerization activity

acetyl-Coenzyme A acetyltransferase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function