inhibitor of CDK, cyclin A1 interacting protein 1

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Synonym

INCA1, HSD45, MGC148151, MGC148150, inhibitor of CDK interacting with cyclin A1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:1.50 cerebellum:- brain stem:1.59 corpus callosum/glia:1.34 pineal gland:1.10 peripheral nerve:- spine:1.59 retina:- eye:- artery/aorta:1.16 vein:0.34 lymphnode:0.32 peripheral blood:- spleen:0.32 thymus:0.28 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:0.69 placenta:0.08 prostate:0.62 ovary:0.56 testis:3.58 heart:0.52 muscle:0.49 esophagus:0.18 stomach:- intestine:0.21 colon:0.34     liver/hepato:0.36    lung:0.25 bladder:0.58 kidney:0.27 pituitary:1.19 thyroid/parathyroid:0.73 adrenal gland:- pancreas:0.58 breast:1.16 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0 ovary:0.14 testis:1.94 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.16 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_213726
Gene ID 388324
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000196388
GTEx ID ENSG00000196388

Orthologous Gene

Mouse[1]  NM_213729
Rat[1]  NM_001108280

Chromosomal Region

17p13.2  [4,891,426  -  4,900,905]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

12477932
15159402
15800920
16148011
18029348
18756329
21540187
21750715
23251661

Gene Ontology  (GO ID)

Biological Process

GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0043065  positive regulation of apoptosis

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0030332  cyclin binding
GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0005515  protein binding