Rho family GTPase 3

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Synonym

RHOE, MemB protein, RhoE, Rho8, memB, Rho-related GTP-binding protein RhoE, Rho family GTPase 3, ARHE, RHO8, RND3, Rnd3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.36 cerebellum:5.59 brain stem:5.97 corpus callosum/glia:5.56 pineal gland:- peripheral nerve:7.91 spine:6.66 retina:- eye:- artery/aorta:8.21 vein:8.96 lymphnode:7.66 peripheral blood:- spleen:8.64 thymus:6.06 bone marrow:5.22 adipose:7.87 bone:- skin:9.05
CAGE cerebrum:2.48 cerebellum:- brain stem:2.58 corpus callosum/glia:1.63 pineal gland:3.55 peripheral nerve:- spine:3.10 retina:- eye:- artery/aorta:3.93 vein:2.46 lymphnode:3.67 peripheral blood:- spleen:4.38 thymus:1.46 bone marrow:- adipose:4.77 bone:- skin:-
RNA-seq cerebrum:1.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.19 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.98 placenta:8.29 prostate:8.97 ovary:7.37 testis:6.17 heart:7.92 muscle:7.14 esophagus:9.70 stomach:7.24 intestine:7.27 colon:7.05 liver/hepato:8.50 lung:8.01 bladder:- kidney:6.28 pituitary:5.61 thyroid/parathyroid:6.51 adrenal gland:8.55 pancreas:5.53 breast:9.30 salivary:6.84
CAGE uterus:3.92 placenta:4.38 prostate:4.34 ovary:3.15 testis:2.57 heart:3.77 muscle:2.83 esophagus:4.46 stomach:- intestine:3.85 colon:3.64     liver/hepato:4.89    lung:3.54 bladder:4.13 kidney:3.31 pituitary:2.94 thyroid/parathyroid:2.83 adrenal gland:- pancreas:1.59 breast:4.03 salivary:2.88
RNA-seq uterus:- placenta:- prostate:4.02 ovary:2.42 testis:2.62 heart:3.51 muscle:1.88 esophagus:- stomach:- intestine:- colon:3.79     liver/hepato:4.36        lung:4.74    bladder:- kidney:3.56 pituitary:- thyroid/parathyroid:3.92 adrenal gland:4.18 pancreas:- breast:4.82 salivary:-

Gene Information

IDs

Refseq ID NM_005168
Gene ID 390
Unigene ID -
Probe set ID 212724_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000115963
GTEx ID ENSG00000115963

Orthologous Gene

Mouse[2]  NM_028810
Rat[1]  NM_001007641

Chromosomal Region

2q23.3  [151,324,709  -  151,395,525]

Gene Family (Interpro ID)

IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

8649376
8889548
9531558
11940653
12163169
12477932
12730235
12773565
12842009
15489334
15754346
15777789
15778465
16311049
17174923
17182035
18045987
18204440
18721871
18923151
18946488
19101510
19244113
19850923
20683643
21109974
21139048
21209796
21478267
21917148
22037464
22132820
22213123
22234932
22238593
22251971
22272352
22357615
22454524
22477709
22807448
22829315
23333304
23472165
23546594
23622247
23630292
24045951
24525741
24667864

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0007155  cell adhesion
GO:0006184  GTP catabolic process
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0000139  Golgi membrane

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity