laminin, alpha 5

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Synonym

Laminin alpha-5 chain precursor, KIAA0533, LAMA5, laminin, alpha 5, KIAA1907

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:30.80 cerebellum:88.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:214.70 spine:112.30 retina:- eye:105.80 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:75.60 thymus:77.30 bone marrow:- adipose:40.30 bone:25.60 skin:28.80
GeneChip cerebrum:6.24 cerebellum:7.62 brain stem:6.06 corpus callosum/glia:6 pineal gland:- peripheral nerve:6.77 spine:6.17 retina:- eye:- artery/aorta:8.30 vein:7.59 lymphnode:7.21 peripheral blood:- spleen:7.08 thymus:6.61 bone marrow:6.14 adipose:7.26 bone:- skin:7.70
CAGE cerebrum:2.63 cerebellum:- brain stem:2.57 corpus callosum/glia:2.52 pineal gland:2.75 peripheral nerve:- spine:2.94 retina:- eye:- artery/aorta:4.79 vein:3.58 lymphnode:3.11 peripheral blood:- spleen:3.20 thymus:2.08 bone marrow:- adipose:4.27 bone:- skin:-
RNA-seq cerebrum:0.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.75 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:87.40 prostate:112.60 ovary:- testis:34.60 heart:63.90 muscle:- esophagus:- stomach:21.20 intestine:64.80 colon:118.70     liver/hepato:31.70        lung:73.30    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:204.50 breast:37.20 salivary:-
GeneChip uterus:7.64 placenta:7.97 prostate:7.48 ovary:6.89 testis:6.33 heart:7.07 muscle:5.97 esophagus:7.72 stomach:7.43 intestine:7.17 colon:7.04 liver/hepato:7.20 lung:8.13 bladder:- kidney:7.60 pituitary:6.62 thyroid/parathyroid:7.81 adrenal gland:6.91 pancreas:7.26 breast:7.79 salivary:6.92
CAGE uterus:4.24 placenta:4.54 prostate:3.98 ovary:3.20 testis:2.58 heart:4.08 muscle:3.39 esophagus:4.04 stomach:- intestine:3.24 colon:4.26     liver/hepato:3.05    lung:4.23 bladder:4.12 kidney:3.94 pituitary:2.52 thyroid/parathyroid:4.00 adrenal gland:- pancreas:3.20 breast:4.04 salivary:3.45
RNA-seq uterus:- placenta:- prostate:2.97 ovary:1.70 testis:1.80 heart:1.57 muscle:0.93 esophagus:- stomach:- intestine:- colon:2.45     liver/hepato:1.12        lung:2.86    bladder:- kidney:2.62 pituitary:- thyroid/parathyroid:2.81 adrenal gland:2.99 pancreas:- breast:2.22 salivary:-

Gene Information

IDs

Refseq ID NM_005560
Gene ID 3911
Unigene ID Hs.473256
Probe set ID 210150_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130702
GTEx ID ENSG00000130702

Orthologous Gene

Mouse[2]  NM_001081171
Rat [0]  

Chromosomal Region

20q13.33  [60,883,011  -  60,942,368]

Gene Family (Interpro ID)

IPR008985  Concanavalin A-like lectin/glucanase
IPR013320  Concanavalin A-like lectin/glucanase, subgroup
IPR000034  Laminin B type IV
IPR018031  Laminin B, subgroup
IPR001791  Laminin G

Link to Pubmed  (Pubmed ID)

7499364
9006922
9245798
9271224
9353324
9597096
9628581
10207021
10617638
10620696
10671376
10956663
10964500
10964957
11104726
11133776
11159210
11311202
11352943
11572484
11780052
11821406
11891225
11964076
11985661
12242717
12244066
12366691
12379663
12382139
12393739
12477932
12682087
12691260
12743034
12817023
14557481
14691145
15231748
15302884
15579904
15774758
15967115
15975931
16169070
16226104
16236823
16289162
16339173
16460839
16581764
16723698
16940506
17888902
18496706
18523231
18635166
18654987
18694491
19056867
19615022
19752234
19913121
20019771
20433883
20628086
20819124
20951195
20972440
21067603
21195710
21461966
21858073
21890473
21921666
21963094
22099024
22268729
22666383
23022198
23264881
23535732
23715200
24036115

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060445  branching involved in salivary gland morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0008283  cell proliferation
GO:0008037  cell recognition
GO:0042384  cilium assembly
GO:0007010  cytoskeleton organization
GO:0009790  embryonic development
GO:0045446  endothelial cell differentiation
GO:0090002  establishment of protein localization in plasma membrane
GO:0030198  extracellular matrix organization
GO:0048041  focal adhesion formation
GO:0001942  hair follicle development
GO:0007229  integrin-mediated signaling pathway
GO:0030324  lung development
GO:0001738  morphogenesis of a polarized epithelium
GO:0016331  morphogenesis of embryonic epithelium
GO:0007517  muscle organ development
GO:0001755  neural crest cell migration
GO:0042475  odontogenesis of dentine-containing tooth
GO:0030155  regulation of cell adhesion
GO:0030334  regulation of cell migration
GO:0042127  regulation of cell proliferation
GO:0045995  regulation of embryonic development
GO:0034446  substrate adhesion-dependent cell spreading

Cellular Component

GO:0005605  basal lamina
GO:0005604  basement membrane
GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0005606  laminin-1 complex
GO:0043259  laminin-10 complex
GO:0043260  laminin-11 complex

Molecular Function

GO:0005178  integrin binding
GO:0005198  structural molecule activity