aryl hydrocarbon receptor nuclear translocator

Synonym

Aryl hydrocarbon receptor nuclear translocator, ARNT, aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 1 beta, HIF-1 beta, HIF-1beta, Dioxin receptor, nuclear translocator, ARNT protein, HIF1BETA, TANGO, HIF1B

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:33.20

cerebellum:12.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:30.70

spine:-

retina:237.30

eye:52.90

artery/aorta:30

vein:-

lymphnode:30.30

peripheral blood:36.40

spleen:56.70

thymus:38.70

bone marrow:59

adipose:80.70

bone:38.40

skin:62.40

GeneChip

cerebrum:5.06

cerebellum:5.27

brain stem:5.10

corpus callosum/glia:5.13

pineal gland:-

peripheral nerve:5.52

spine:5.06

retina:-

eye:-

artery/aorta:5.77

vein:5.62

lymphnode:5.43

peripheral blood:-

spleen:5.71

thymus:5.53

bone marrow:5.44

adipose:5.62

bone:-

skin:5.74

CAGE

cerebrum:3.15

cerebellum:-

brain stem:3.17

corpus callosum/glia:3.57

pineal gland:4.08

peripheral nerve:-

spine:3.39

retina:-

eye:-

artery/aorta:3.91

vein:3.45

lymphnode:3.35

peripheral blood:-

spleen:3.57

thymus:3.38

bone marrow:-

adipose:3.70

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.41

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:76.50

prostate:33.80

ovary:-

testis:69.20

heart:38.30

muscle:-

esophagus:-

stomach:63.70

intestine:-

colon:17

liver/hepato:52.80

lung:39.10

bladder:125.60

kidney:93.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:53.30

breast:65.10

salivary:-

GeneChip

uterus:6.11

placenta:5.62

prostate:5.80

ovary:6.16

testis:5.87

heart:5.51

muscle:5.64

esophagus:5.56

stomach:5.48

intestine:5.29

colon:5.57

liver/hepato:5.87

lung:5.69

bladder:-

kidney:5.45

pituitary:5.26

thyroid/parathyroid:5.79

adrenal gland:5.68

pancreas:5.24

breast:6.01

salivary:5.47

CAGE

uterus:4.00

placenta:4.00

prostate:3.61

ovary:3.98

testis:3.54

heart:3.67

muscle:3.47

esophagus:3.46

stomach:-

intestine:3.34

colon:3.40

liver/hepato:3.43

lung:3.76

bladder:3.76

kidney:3.26

pituitary:3.53

thyroid/parathyroid:3.36

adrenal gland:-

pancreas:3.63

breast:3.86

salivary:3.40

RNA-seq

uterus:-

placenta:-

prostate:0.81

ovary:0.00

testis:1.75

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.84

lung:1.94

bladder:-

kidney:2.20

pituitary:-

thyroid/parathyroid:1.90

adrenal gland:0.94

pancreas:-

breast:1.17

salivary:-

IDs

Refseq ID	NM_178427
Gene ID	405
Unigene ID	Hs.632446
Probe set ID	218221_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000143437
GTEx ID	ENSG00000143437

Orthologous Gene

Mouse[2]	NM_001037737, NM_009709
Rat [0]

Chromosomal Region

1q21.3 [150,782,181 - 150,849,244]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000014

PAS

Gene Ontology (GO ID)

Biological Process

GO:0030154	cell differentiation
GO:0071456	cellular response to hypoxia
GO:0001892	embryonic placenta development
GO:0042789	mRNA transcription from RNA polymerase II promoter
GO:0001938	positive regulation of endothelial cell proliferation
GO:0045648	positive regulation of erythrocyte differentiation
GO:0045821	positive regulation of glycolysis
GO:0046886	positive regulation of hormone biosynthetic process
GO:0033235	positive regulation of protein sumoylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0001666	response to hypoxia
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0004874	aryl hydrocarbon receptor activity
GO:0017162	aryl hydrocarbon receptor binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003713	transcription coactivator activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

aryl hydrocarbon receptor nuclear translocator

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function