lactotransferrin

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Synonym

Lactotransferrin precursor, LTF, lactotransferrin, Talalactoferrin alfa, HLF2, GIG12, LF, Lactoferrin

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:20.10

cerebellum:-

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:693.50

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:1330

spleen:75.60

thymus:206.10

bone marrow:6691.30

adipose:-

bone:76.80

skin:388.80

GeneChip

cerebrum:4.47

cerebellum:4.33

brain stem:4.50

corpus callosum/glia:5.35

pineal gland:-

peripheral nerve:4.31

spine:5.37

retina:-

eye:-

artery/aorta:4.88

vein:4.58

lymphnode:7.34

peripheral blood:-

spleen:6.51

thymus:7.02

bone marrow:12.37

adipose:5.35

bone:-

skin:5.93

CAGE

cerebrum:0.66

cerebellum:-

brain stem:0.71

corpus callosum/glia:3.06

pineal gland:0.51

peripheral nerve:-

spine:0.64

retina:-

eye:-

artery/aorta:5.78

vein:2.95

lymphnode:3.78

peripheral blood:-

spleen:3.21

thymus:3.07

bone marrow:-

adipose:0.96

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.41

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:54.70

placenta:7.30

prostate:1554.50

ovary:-

testis:60.60

heart:-

muscle:20.10

esophagus:-

stomach:1210.80

intestine:-

colon:25.40

liver/hepato:-

lung:13836.70

bladder:251.20

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:334.50

salivary:8538.60

GeneChip

uterus:4.82

placenta:4.95

prostate:7.51

ovary:4.60

testis:4.24

heart:4.56

muscle:4.66

esophagus:6.24

stomach:9.83

intestine:6.48

colon:6.58

liver/hepato:4.74

lung:5.89

bladder:-

kidney:4.91

pituitary:5.16

thyroid/parathyroid:6.68

adrenal gland:4.31

pancreas:5.51

breast:9.12

salivary:10.51

CAGE

uterus:3.27

placenta:1.79

prostate:4.44

ovary:1.29

testis:2.22

heart:2.20

muscle:1.23

esophagus:1.78

stomach:-

intestine:0.57

colon:1.24

liver/hepato:0.84

lung:3.99

bladder:2.75

kidney:4.80

pituitary:1.68

thyroid/parathyroid:1.32

adrenal gland:-

pancreas:1.74

breast:4.44

salivary:7.13

RNA-seq

uterus:-

placenta:-

prostate:3.43

ovary:0.00

testis:3.90

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:5.97

bladder:-

kidney:2.32

pituitary:-

thyroid/parathyroid:0.62

adrenal gland:0.66

pancreas:-

breast:4.87

salivary:-

IDs

Refseq ID	NM_002343
Gene ID	4057
Unigene ID	Hs.529517
Probe set ID	202018_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000012223
GTEx ID	ENSG00000012223

Orthologous Gene

Mouse[1]	NM_008522
Rat [0]

Chromosomal Region

3p21.31 [46,477,136 - 46,526,724]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001156	Peptidase S60, transferrin lactoferrin
IPR016357	Transferrin

Gene Ontology (GO ID)

Biological Process

GO:0019732	antifungal humoral response
GO:0042742	defense response to bacterium
GO:0006959	humoral immune response
GO:0051701	interaction with host
GO:0033214	iron assimilation by chelation and transport
GO:0006826	iron ion transport
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0001503	ossification
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
GO:0006508	proteolysis
GO:0001817	regulation of cytokine production
GO:0032680	regulation of tumor necrosis factor production
GO:0052572	response to host immune response
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005576	extracellular region
GO:0005634	nucleus
GO:0030141	secretory granule

Molecular Function

GO:0003677	DNA binding
GO:0008199	ferric iron binding
GO:0008201	heparin binding
GO:0005515	protein binding
GO:0043539	protein serine/threonine kinase activator activity
GO:0004252	serine-type endopeptidase activity

lactotransferrin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function