mannose-6-phosphate receptor (cation dependent)

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Synonym

M6PR, SMPR, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPRD, MPR 46, MPR46, mannose-6-phosphate receptor (cation dependent), CD Man-6-P receptor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:156.40 cerebellum:63 brain stem:- corpus callosum/glia:145.80 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:58.80 artery/aorta:239.80 vein:- lymphnode:70.80 peripheral blood:437.20 spleen:283.60 thymus:154.60 bone marrow:19.70 adipose:- bone:127.90 skin:163.20
GeneChip cerebrum:6.87 cerebellum:6.53 brain stem:6.73 corpus callosum/glia:6.97 pineal gland:- peripheral nerve:6.99 spine:6.84 retina:- eye:- artery/aorta:6.34 vein:7.17 lymphnode:7.67 peripheral blood:- spleen:8 thymus:7.83 bone marrow:7.74 adipose:7.13 bone:- skin:6.76
CAGE cerebrum:3.68 cerebellum:- brain stem:3.69 corpus callosum/glia:3.77 pineal gland:4.10 peripheral nerve:- spine:3.70 retina:- eye:- artery/aorta:3.93 vein:4.10 lymphnode:4.20 peripheral blood:- spleen:4.48 thymus:4.02 bone marrow:- adipose:4.11 bone:- skin:-
RNA-seq cerebrum:4.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.61 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:61.90 prostate:202.80 ovary:74.50 testis:147.10 heart:153.30 muscle:- esophagus:- stomach:42.50 intestine:194.40 colon:93.30     liver/hepato:21.10        lung:176    bladder:376.80 kidney:83.20 pituitary:- thyroid/parathyroid:327.50 adrenal gland:152.40 pancreas:- breast:55.80 salivary:328.40
GeneChip uterus:7.35 placenta:7.24 prostate:7.32 ovary:7.84 testis:7.34 heart:7.42 muscle:6.85 esophagus:7.22 stomach:7.47 intestine:7.42 colon:7.26 liver/hepato:7.02 lung:8.28 bladder:- kidney:7.48 pituitary:6.30 thyroid/parathyroid:7.76 adrenal gland:6.91 pancreas:7.30 breast:7.35 salivary:7.56
CAGE uterus:3.87 placenta:3.93 prostate:3.88 ovary:3.85 testis:4.15 heart:3.94 muscle:3.52 esophagus:3.82 stomach:- intestine:3.70 colon:3.89     liver/hepato:4.22    lung:4.17 bladder:3.84 kidney:4.08 pituitary:3.46 thyroid/parathyroid:4.27 adrenal gland:- pancreas:4.07 breast:4.01 salivary:4.32
RNA-seq uterus:- placenta:- prostate:5.40 ovary:5.49 testis:5.14 heart:4.58 muscle:4.32 esophagus:- stomach:- intestine:- colon:4.96     liver/hepato:4.62        lung:5.35    bladder:- kidney:5.38 pituitary:- thyroid/parathyroid:5.80 adrenal gland:5.12 pancreas:- breast:4.83 salivary:-

Gene Information

IDs

Refseq ID NM_002355
Gene ID 4074
Unigene ID Hs.134084
Probe set ID 200900_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000003056
GTEx ID ENSG00000003056

Orthologous Gene

Mouse[2]  NM_010749
Rat[1]  NM_001007700

Chromosomal Region

12p13.31  [9,092,959  -  9,102,551]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1849818
2172972
2441386
2960682
7640295
8099077
8125298
8674621
9590177
9604938
10799489
10829017
11106728
11387475
11859375
11886874
12223278
12477932
12493773
12697764
14702039
15044437
15078902
15167696
15469932
15489334
15620351
16751776
17207965
17210618
17255364
18003638
18088323
18367545
18621992
19345684
19801188
19928875
19946888
20351714
21139048
22015004
22163010
22268729
22768187
22939629
24407285

Gene Ontology  (GO ID)

Biological Process

GO:0008333  endosome to lysosome transport
GO:0006898  receptor-mediated endocytosis

Cellular Component

GO:0009986  cell surface
GO:0005768  endosome
GO:0005887  integral to plasma membrane
GO:0005770  late endosome
GO:0005765  lysosomal membrane

Molecular Function

GO:0005537  mannose binding
GO:0015578  mannose transmembrane transporter activity
GO:0004888  transmembrane receptor activity