MAS1 oncogene

 jump to detail

Synonym

MAS1 oncogene, MGC119966, MAS proto-oncogene, MAS, MAS1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.97 cerebellum:4.92 brain stem:5.01 corpus callosum/glia:4.87 pineal gland:- peripheral nerve:5.15 spine:5.13 retina:- eye:- artery/aorta:4.93 vein:5.10 lymphnode:4.73 peripheral blood:- spleen:4.69 thymus:4.39 bone marrow:5.02 adipose:5.08 bone:- skin:4.86
CAGE nodata
RNA-seq cerebrum:0.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.61 placenta:5.11 prostate:4.67 ovary:4.54 testis:4.84 heart:5.14 muscle:5.20 esophagus:4.84 stomach:4.92 intestine:5.12 colon:5.15 liver/hepato:5.04 lung:4.72 bladder:- kidney:4.92 pituitary:5 thyroid/parathyroid:4.84 adrenal gland:4.99 pancreas:5.91 breast:4.68 salivary:5
CAGE nodata
RNA-seq uterus:- placenta:- prostate:0 ovary:0.03 testis:0.06 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_002377
Gene ID 4142
Unigene ID Hs.99900
Probe set ID 208210_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130368
GTEx ID ENSG00000130368

Orthologous Gene

Mouse[1]  NM_008552
Rat [0]  

Chromosomal Region

6q25.3  [160,327,974  -  160,329,108]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR000820  Mas transmembrane protein

Link to Pubmed  (Pubmed ID)

1725048
2197067
3329713
3419518
3708691
8661154
10785460
11967280
12477932
12829792
14574404
15123239
15489334
16611642
17207965
18636314
19164480
19240061
19461648
20361351
20592051
20674894
21316680
22003054
22048948
22164327
22319643
22510001
22518283
22518286
23459756
23592774
24128372
24168260
24583173

Gene Ontology  (GO ID)

Biological Process

GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0009653  anatomical structure morphogenesis
GO:0008283  cell proliferation
GO:0071375  cellular response to peptide hormone stimulus
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0021766  hippocampus development
GO:0008584  male gonad development
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0008284  positive regulation of cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0060732  positive regulation of inositol phosphate biosynthetic process
GO:0070528  protein kinase C signaling cascade
GO:0050727  regulation of inflammatory response
GO:0014823  response to activity
GO:0042493  response to drug
GO:0034698  response to gonadotropin stimulus
GO:0007283  spermatogenesis

Cellular Component

GO:0009986  cell surface
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0001595  angiotensin receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0042277  peptide binding
GO:0017046  peptide hormone binding