Meis homeobox 2

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Synonym

MEIS2, Meis1-related protein 1, MGC2820, Homeobox protein Meis2, Meis (mouse) homolog 2, HsT18361

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:113.80 cerebellum:- brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:135.20 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:18.90 thymus:25.80 bone marrow:- adipose:- bone:- skin:57.60
GeneChip cerebrum:7.53 cerebellum:6.72 brain stem:6.06 corpus callosum/glia:7.10 pineal gland:- peripheral nerve:5.88 spine:7.43 retina:- eye:- artery/aorta:7.99 vein:7.38 lymphnode:6.76 peripheral blood:- spleen:7.16 thymus:7.52 bone marrow:4.58 adipose:6.77 bone:- skin:6.19
CAGE cerebrum:3.51 cerebellum:- brain stem:2.73 corpus callosum/glia:3.03 pineal gland:1.88 peripheral nerve:- spine:3.50 retina:- eye:- artery/aorta:3.97 vein:3.14 lymphnode:2.97 peripheral blood:- spleen:2.85 thymus:2.36 bone marrow:- adipose:2.48 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.34 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:173.20 placenta:14.60 prostate:214 ovary:37.30 testis:8.70 heart:102.20 muscle:- esophagus:- stomach:- intestine:32.40 colon:59.40     liver/hepato:52.80        lung:58.70    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:204.50 breast:74.30 salivary:-
GeneChip uterus:8.51 placenta:5.50 prostate:9.10 ovary:8.31 testis:5.07 heart:7.90 muscle:4.97 esophagus:7.04 stomach:7.81 intestine:7 colon:6.90 liver/hepato:6.53 lung:7.61 bladder:- kidney:7.22 pituitary:8.21 thyroid/parathyroid:6.62 adrenal gland:9.03 pancreas:5.97 breast:7.58 salivary:9.02
CAGE uterus:4.88 placenta:2.18 prostate:4.30 ovary:3.99 testis:2.49 heart:3.84 muscle:1.35 esophagus:3.30 stomach:- intestine:2.90 colon:3.89     liver/hepato:3.13    lung:3.51 bladder:4.34 kidney:3.23 pituitary:4.30 thyroid/parathyroid:1.98 adrenal gland:- pancreas:3.52 breast:3.58 salivary:4.48
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.01 heart:0.47 muscle:0.00 esophagus:- stomach:- intestine:- colon:2.79     liver/hepato:0.22        lung:0.00    bladder:- kidney:1.30 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_170674
Gene ID 4212
Unigene ID Hs.510989
Probe set ID 207480_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000134138
GTEx ID ENSG00000134138

Orthologous Gene

Mouse[12]  NM_001136072, NM_001159567, NM_001159568, NM_001159569, NM_001159570, NM_010825
Rat[1]  NM_001107758, NM_001159567, NM_001159568, NM_001159569, NM_001159570, NM_010825

Chromosomal Region

15q14  [37,183,222  -  37,393,504]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

8889548
9049632
9383298
10619030
10764806
11279116
11438208
11834421
12477932
14702039
14702098
15161102
15489334
15617687
16344560
17178831
18029348
18408019
18821565
18973687
19559479
19584346
20195266
20211142
20379614
20523026
20553494
21368052
21746878
21832049
22028617
23541832
23667531
24002674

Gene Ontology  (GO ID)

Biological Process

GO:0001654  eye development
GO:0045638  negative regulation of myeloid cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006366  transcription from RNA polymerase II promoter

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003712  transcription cofactor activity
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding