methyltransferase like 1

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Synonym

methyltransferase like 1, YDL201w, tRNA(m7G46)-methyltransferase, Methyltransferase-like protein 1, METTL1, methyltransferase-like 1, C12orf1, tRNA (guanine-N(7)-)-methyltransferase, TRM8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:11.80 artery/aorta:30 vein:- lymphnode:20.20 peripheral blood:18.20 spleen:37.80 thymus:- bone marrow:- adipose:- bone:- skin:28.80
GeneChip cerebrum:5.86 cerebellum:5.61 brain stem:6.02 corpus callosum/glia:5.76 pineal gland:- peripheral nerve:6.05 spine:5.76 retina:- eye:- artery/aorta:6.22 vein:6.06 lymphnode:6.17 peripheral blood:- spleen:5.90 thymus:5.38 bone marrow:6.06 adipose:6.15 bone:- skin:6.37
CAGE cerebrum:1.79 cerebellum:- brain stem:1.87 corpus callosum/glia:1.66 pineal gland:2.16 peripheral nerve:- spine:1.75 retina:- eye:- artery/aorta:2.19 vein:2.39 lymphnode:2.26 peripheral blood:- spleen:2.10 thymus:1.53 bone marrow:- adipose:2.52 bone:- skin:-
RNA-seq cerebrum:1.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.95 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:29.10 prostate:- ovary:37.30 testis:13 heart:76.60 muscle:- esophagus:- stomach:- intestine:64.80 colon:8.50     liver/hepato:-        lung:29.30    bladder:125.60 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:6.22 placenta:5.76 prostate:6.27 ovary:6.43 testis:6.24 heart:6.04 muscle:6.02 esophagus:6.46 stomach:6.18 intestine:6.18 colon:6.18 liver/hepato:6.22 lung:6.12 bladder:- kidney:6.61 pituitary:6.31 thyroid/parathyroid:6.27 adrenal gland:6.52 pancreas:6.58 breast:6.30 salivary:6.30
CAGE uterus:2.21 placenta:2.08 prostate:2.04 ovary:2.83 testis:2.37 heart:2.43 muscle:2.87 esophagus:1.80 stomach:- intestine:1.78 colon:2.08     liver/hepato:2.59    lung:2.05 bladder:2.24 kidney:2.81 pituitary:2.40 thyroid/parathyroid:2.65 adrenal gland:- pancreas:3.45 breast:2.19 salivary:2.26
RNA-seq uterus:- placenta:- prostate:2.45 ovary:3.53 testis:2.99 heart:1.29 muscle:2.91 esophagus:- stomach:- intestine:- colon:1.97     liver/hepato:2.28        lung:2.08    bladder:- kidney:3.42 pituitary:- thyroid/parathyroid:2.93 adrenal gland:3.27 pancreas:- breast:2.25 salivary:-

Gene Information

IDs

Refseq ID NM_005371
Gene ID 4234
Unigene ID Hs.42957
Probe set ID 204027_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000037897
GTEx ID ENSG00000037897

Orthologous Gene

Mouse[1]  NM_010792
Rat[1]  NM_010792

Chromosomal Region

12q14.1  [58,162,254  -  58,166,576]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7566098
8125298
10329009
12403464
12477932
12539042
15489334
15861136
16189514
18029348
19525955
19692168
19913121
20394945
20628086
21890473
21906983
22863883
22939629
23000965
23349634

Gene Ontology  (GO ID)

Biological Process

GO:0006400  tRNA modification

Cellular Component

GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0008176  tRNA (guanine-N7-)-methyltransferase activity
GO:0000049  tRNA binding