class II, major histocompatibility complex, transactivator

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Synonym

MHC2TA, C2TA, MHC class II transactivator, CIITA IV, CIITA

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.39

cerebellum:4.67

brain stem:4.31

corpus callosum/glia:4.32

pineal gland:-

peripheral nerve:4.17

spine:4.09

retina:-

eye:-

artery/aorta:4.35

vein:4.58

lymphnode:4.30

peripheral blood:-

spleen:4.28

thymus:4.26

bone marrow:4.20

adipose:4.31

bone:-

skin:4.53

CAGE

cerebrum:1.76

cerebellum:-

brain stem:2.76

corpus callosum/glia:3.31

pineal gland:1.14

peripheral nerve:-

spine:3.08

retina:-

eye:-

artery/aorta:2.48

vein:4.85

lymphnode:4.43

peripheral blood:-

spleen:4.22

thymus:3.12

bone marrow:-

adipose:2.52

bone:-

skin:-

RNA-seq

cerebrum:0.32

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.57

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.75

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:4.13

placenta:4

prostate:4.03

ovary:4.16

testis:3.89

heart:4.26

muscle:4.50

esophagus:4.21

stomach:4.05

intestine:4.20

colon:4.30

liver/hepato:4.18

lung:4.15

bladder:-

kidney:4.09

pituitary:4.25

thyroid/parathyroid:3.99

adrenal gland:4.14

pancreas:4.74

breast:4.10

salivary:4.49

CAGE

uterus:2.15

placenta:1.25

prostate:2.27

ovary:1.53

testis:1.26

heart:1.75

muscle:1.59

esophagus:2.35

stomach:-

intestine:1.50

colon:1.70

liver/hepato:1.01

lung:2.99

bladder:2.31

kidney:1.42

pituitary:1.27

thyroid/parathyroid:0.79

adrenal gland:-

pancreas:0.94

breast:0.55

salivary:2.78

RNA-seq

uterus:-

placenta:-

prostate:0.96

ovary:0.95

testis:0.50

heart:0.56

muscle:0.28

esophagus:-

stomach:-

intestine:-

colon:0.22

liver/hepato:0.16

lung:1.97

bladder:-

kidney:0.93

pituitary:-

thyroid/parathyroid:0.35

adrenal gland:2.71

pancreas:-

breast:0.99

salivary:-

IDs

Refseq ID	NM_000246
Gene ID	4261
Unigene ID	-
Probe set ID	211884_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000179583
GTEx ID	ENSG00000179583

Orthologous Gene

Mouse[2]	NM_007575
Rat[1]	NM_053529

Chromosomal Region

16p13.13 [10,971,039 - 11,023,624]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_49 [5,001 - 52,786]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0006955	immune response
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0032966	negative regulation of collagen biosynthetic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045345	positive regulation of MHC class I biosynthetic process
GO:0045348	positive regulation of MHC class II biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0046677	response to antibiotic
GO:0034341	response to interferon-gamma
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005654	nucleoplasm
GO:0016605	PML body

Molecular Function

GO:0005524	ATP binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0032403	protein complex binding
GO:0033613	transcription activator binding
GO:0003713	transcription coactivator activity

class II, major histocompatibility complex, transactivator

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function