macrophage migration inhibitory factor (glycosylation-inhibiting factor)

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Synonym

Glycosylation-inhibiting factor, GLIF, MMIF

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:109 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:445 peripheral nerve:30.70 spine:- retina:593.20 eye:293.80 artery/aorta:119.90 vein:733.10 lymphnode:323.50 peripheral blood:72.90 spleen:75.60 thymus:64.40 bone marrow:59 adipose:242 bone:38.40 skin:148.80
GeneChip cerebrum:9.73 cerebellum:8.75 brain stem:9.93 corpus callosum/glia:9.03 pineal gland:- peripheral nerve:9.35 spine:9.83 retina:- eye:- artery/aorta:9.43 vein:9.27 lymphnode:9.49 peripheral blood:- spleen:8.89 thymus:9.67 bone marrow:8.46 adipose:8.97 bone:- skin:9.95
CAGE cerebrum:6.02 cerebellum:- brain stem:5.47 corpus callosum/glia:4.99 pineal gland:5.60 peripheral nerve:- spine:6.44 retina:- eye:- artery/aorta:6.27 vein:6.04 lymphnode:6.33 peripheral blood:- spleen:5.44 thymus:5.39 bone marrow:- adipose:4.98 bone:- skin:-
RNA-seq cerebrum:6.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:7.38 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:191.40 placenta:193.10 prostate:169 ovary:- testis:129.80 heart:332.10 muscle:20.10 esophagus:- stomach:- intestine:97.20 colon:76.30     liver/hepato:52.80        lung:141.70    bladder:- kidney:187.10 pituitary:347.90 thyroid/parathyroid:- adrenal gland:203.10 pancreas:195.60 breast:27.90 salivary:-
GeneChip uterus:9.51 placenta:9.64 prostate:10.60 ovary:10.23 testis:9.36 heart:9.12 muscle:7.16 esophagus:10.30 stomach:9.10 intestine:9.34 colon:9.48 liver/hepato:9.60 lung:9.02 bladder:- kidney:10.42 pituitary:10.07 thyroid/parathyroid:9.87 adrenal gland:9.88 pancreas:9.83 breast:9.91 salivary:9.22
CAGE uterus:5.14 placenta:5.89 prostate:5.53 ovary:5.51 testis:5.79 heart:6.31 muscle:5.27 esophagus:6.10 stomach:- intestine:5.05 colon:5.89     liver/hepato:6.46    lung:6.12 bladder:5.62 kidney:5.95 pituitary:6.06 thyroid/parathyroid:5.86 adrenal gland:- pancreas:6.83 breast:6.86 salivary:5.49
RNA-seq uterus:- placenta:- prostate:7.70 ovary:7.49 testis:7.71 heart:5.44 muscle:5.27 esophagus:- stomach:- intestine:- colon:7.39     liver/hepato:6.85        lung:7.33    bladder:- kidney:7.93 pituitary:- thyroid/parathyroid:7.73 adrenal gland:7.73 pancreas:- breast:6.83 salivary:-

IDs

Refseq ID NM_002415
Gene ID 4282
Unigene ID Hs.407995
Probe set ID 217871_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000240972
GTEx ID ENSG00000240972

Orthologous Gene

Mouse[1]  NM_010798
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1286669
2552447
3917866
7558020
7679497
7683862
7947826
8188240
8234256
8289313
8601455
8610159
8643551
8647256
8766818
8988336
9002552
9006339
9027512
10334104
10353846
10562313
11089976
11170644
11259268
11508429
11875000
11920501
11978887
11985788
11997397
12009356
12032852
12070782
12109441
12126556
12180727
12186913
12218292
12218308
12235522
12355488
12402212
12445161
12477932
12480958
12507885
12576459
12607777
12612911
12615835
12626594
12631237
12665801
12667094
12681488
12738641
12740374
12746913
12782713
12796500
12822893
12847682
12965208
14502271
14551601
14581488
14607690
14736878
14760795
14962818
15018649
15065001
15146413
15146431
15170913
15216464
15231747
15286457
15292349
15304087
15308783
15461802
15472203
15489334
15545061
15545824
15576462
15585204
15585220
15592455
15612021
15630728
15659324
15757663
15800984
15815686
15820792
15838879
15910495
15910597
16000172
16051683
16085663
16115023
16133063
16169070
16179637
16189514
16200611
16205314
16220288
16224818
16243796
16247506
16285950
16314470
16314559
16317091
16369812
16385258
16388506
16488392
16527487
16538639
16677407
16709839
16724072
16767681
16780713
16807115
16820919
16839849
16854377
16861224
16872482
16893895
16929348
17005573
17029206
17045821
17075815
17108334
17142775
17166737
17172590
17181929
17206642
17215861
17224449
17353931
17435771
17438452
17438455
17495357
17526494
17541237
17559578
17591062
17592555
17620429
17658526
17706208
17709373
17712545
17728788
17763209
17786285
17854804
17854909
17869648
17906677
17912466
18034423
18037272
18054247
18060744
18074864
18078632
18081874
18097599
18165264
18171527
18171602
18177450
18228042
18235500
18239193
18242614
18261992
18270460
18356846
18362243
18426738
18466513
18469521
18474653
18490733
18493321
18502749
18618071
18676531
18677096
18680514
18684922
18710704
18720262
18795803
18815136
18832726
18842989
18852457
18853133
18930766
19009023
19038405
19056867
19062717
19081768
19109179
19155217
19157791
19167373
19170716
19188484
19196797
19260777
19299454
19317738
19346297
19376177
19394321
19406662
19417556
19423540
19428548
19454686
19464392
19475570
19591577
19601712
19602265
19644855
19665027
19720544
19723024
19724898
19726058
19737008
19738201
19747950
19759012
19762145
19773451
19776019
19776337
19799813
19829123
19913121
19938192
19941661
19950249
20038293
20085845
20127054
20149326
20178462
20193596
20200619
20203087
20233515
20237496
20303284
20346241
20369477
20380014
20382217
20383199
20406964
20438785
20439102
20447688
20448056
20452482
20460119
20467327
20471506
20499270
20534506
20546256
20573157
20598902
20621719
20628086
20646540
20673868
20805296
20807568
20811626
20829434
20847814
20861157
20863520
20872800
20878093
20944103
20980171
21030269
21045753
21071513
21087445
21106938
21139048
21162929
21169549
21208809
21209875
21269946
21281800
21283538
21283592
21319273
21360573
21401926
21417823
21512965
21515791
21553324
21575460
21607559
21607712
21623990
21641401
21684012
21725855
21750916
21773885
21792010
21817065
21823060
21848392
21852299
21875883
21890178
21890473
21906983
21942715
21963094
21988832
21990375
22001757
22007254
22053931
22079264
22099602
22127710
22166284
22174124
22206839
22271573
22302395
22327470
22415145
22430150
22449335
22451332
22461895
22505724
22543583
22609310
22611320
22623428
22649515
22676646
22693633
22742858
22759564
22782901
22810585
22813781
22820623
22883521
22892326
22893706
22898393
22909194
22927777
22939113
22939629
22949182
22952837
22988252
23000965
23023114
23028743
23043599
23050964
23060578
23064787
23068083
23125447
23179933
23207293
23246423
23272137
23315862
23354841
23383040
23402792
23403077
23410506
23411097
23451183
23497377
23523092
23526214
23537651
23552723
23566229
23707797
23728617
23770720
23776208
23794947
23846621
23882081
23895962
23913513
23978362
23985752
24003215
24039418
24066864
24138931
24151396
24158957
24167613
24194192
24273891
24337577
24356968
24379579
24441872
24583282
24654937
24683185
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0019752  carboxylic acid metabolic process
GO:0007569  cell aging
GO:0008283  cell proliferation
GO:0007166  cell surface receptor linked signal transduction
GO:0030330  DNA damage response, signal transduction by p53 class mediator
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0043066  negative regulation of apoptosis
GO:0071157  negative regulation of cell cycle arrest
GO:0032269  negative regulation of cellular protein metabolic process
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0010629  negative regulation of gene expression
GO:0002906  negative regulation of mature B cell apoptosis
GO:0033033  negative regulation of myeloid cell apoptosis
GO:0050918  positive chemotaxis
GO:0030890  positive regulation of B cell proliferation
GO:0050715  positive regulation of cytokine secretion
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0031666  positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043406  positive regulation of MAP kinase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0042327  positive regulation of phosphorylation
GO:0010739  positive regulation of protein kinase A signaling cascade
GO:0001516  prostaglandin biosynthetic process
GO:0070207  protein homotrimerization
GO:0043030  regulation of macrophage activation

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0005126  cytokine receptor binding
GO:0004167  dopachrome isomerase activity
GO:0050178  phenylpyruvate tautomerase activity
GO:0005515  protein binding
GO:0005102  receptor binding