achaete-scute complex homolog 1 (Drosophila)

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Synonym

MASH1, HASH1, Achaete-scute homolog 1, ASH1, achaete-scute complex-like 1 (Drosophila), ASCL1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.74 cerebellum:4.29 brain stem:5.31 corpus callosum/glia:6.05 pineal gland:- peripheral nerve:3.42 spine:6.56 retina:- eye:- artery/aorta:3.63 vein:3.73 lymphnode:3.57 peripheral blood:- spleen:3.27 thymus:6.02 bone marrow:3.68 adipose:3.59 bone:- skin:3.74
CAGE cerebrum:3.17 cerebellum:- brain stem:2.83 corpus callosum/glia:3.32 pineal gland:1.81 peripheral nerve:- spine:3.76 retina:- eye:- artery/aorta:1.16 vein:1.76 lymphnode:0.06 peripheral blood:- spleen:0 thymus:2.43 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:2.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.72 placenta:3.56 prostate:3.76 ovary:3.56 testis:3.63 heart:3.45 muscle:3.73 esophagus:3.51 stomach:3.79 intestine:3.50 colon:3.36 liver/hepato:3.49 lung:3.74 bladder:- kidney:3.37 pituitary:7.52 thyroid/parathyroid:3.47 adrenal gland:4.12 pancreas:4.10 breast:3.58 salivary:3.46
CAGE uterus:0.13 placenta:0 prostate:0.39 ovary:0.52 testis:0.50 heart:0.08 muscle:0 esophagus:0 stomach:- intestine:0.14 colon:0     liver/hepato:1.60    lung:0.44 bladder:0.09 kidney:0 pituitary:3.47 thyroid/parathyroid:0.17 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.02 ovary:0.18 testis:0.47 heart:0.02 muscle:0.04 esophagus:- stomach:- intestine:- colon:0.07     liver/hepato:0.72        lung:0.03    bladder:- kidney:0.10 pituitary:- thyroid/parathyroid:0.09 adrenal gland:0.04 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_004316
Gene ID 429
Unigene ID -
Probe set ID 209987_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000139352
GTEx ID ENSG00000139352

Orthologous Gene

Mouse[1]  NM_008553
Rat[1]  NM_022384

Chromosomal Region

12q23.2  [103,351,464  -  103,354,294]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8390674
8595908
8662987
8900141
8948587
9126746
9186001
9197246
10656681
10903890
11171979
11309412
11564735
11736660
11825874
11940670
11948117
12000752
12050665
12477932
12858003
14532329
14668716
14759067
15240857
15272537
15489334
15492808
15701827
16021468
16029117
16103883
16160079
16344560
16899352
17507989
17923682
18311112
18339843
18491256
18585058
18587321
18587322
18802035
19008346
19097999
19176379
19744316
20097173
20124469
20206680
20301600
20515335
20538960
20659153
20677557
20842449
21300955
21495212
21573214
21684625
21737174
21856745
22172490
22422124
23300791
23375646
23530560
23657976
23707066
23739064
23739972

Gene Ontology  (GO ID)

Biological Process

GO:0071259  cellular response to magnetism
GO:0021954  central nervous system neuron development
GO:0021987  cerebral cortex development
GO:0021892  cerebral cortex GABAergic interneuron differentiation
GO:0021879  forebrain neuron differentiation
GO:0060487  lung epithelial cell differentiation
GO:0043066  negative regulation of apoptosis
GO:0045665  negative regulation of neuron differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007400  neuroblast fate determination
GO:0007405  neuroblast proliferation
GO:0022008  neurogenesis
GO:0048665  neuron fate specification
GO:0001764  neuron migration
GO:0003359  noradrenergic neuron fate commitment
GO:0007219  Notch signaling pathway
GO:0060166  olfactory pit development
GO:0014003  oligodendrocyte development
GO:0007389  pattern specification process
GO:0045787  positive regulation of cell cycle
GO:0050769  positive regulation of neurogenesis
GO:0043525  positive regulation of neuron apoptosis
GO:0045666  positive regulation of neuron differentiation
GO:0045747  positive regulation of Notch signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060165  regulation of timing of subpallium neuron differentiation
GO:0070849  response to epidermal growth factor stimulus
GO:0051593  response to folic acid
GO:0010226  response to lithium ion
GO:0032526  response to retinoic acid
GO:0021527  spinal cord association neuron differentiation
GO:0021530  spinal cord oligodendrocyte cell fate specification
GO:0060163  subpallium neuron fate commitment
GO:0048485  sympathetic nervous system development
GO:0006351  transcription, DNA-dependent
GO:0021750  vestibular nucleus development

Cellular Component

GO:0043025  cell soma
GO:0005634  nucleus

Molecular Function

GO:0043425  bHLH transcription factor binding
GO:0003677  DNA binding
GO:0003690  double-stranded DNA binding
GO:0070888  E-box binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity