acetylcholinesterase (Yt blood group)

Synonym

N-ACHE, acetylcholinesterase (YT blood group), AChE, ACHE, Acetylcholinesterase precursor, ARACHE, acetylcholinesterase (Yt blood group), YT

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:103.10

cerebellum:113.30

brain stem:-

corpus callosum/glia:87.50

pineal gland:296.70

peripheral nerve:-

spine:336.90

retina:-

eye:70.50

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:18.90

thymus:38.70

bone marrow:-

adipose:-

bone:-

skin:19.20

GeneChip

cerebrum:5.83

cerebellum:6.19

brain stem:6.90

corpus callosum/glia:5.11

pineal gland:-

peripheral nerve:7.57

spine:6.13

retina:-

eye:-

artery/aorta:5.05

vein:5.22

lymphnode:5.50

peripheral blood:-

spleen:4.83

thymus:5.11

bone marrow:6.06

adipose:5.21

bone:-

skin:5.27

CAGE

cerebrum:3.23

cerebellum:-

brain stem:2.89

corpus callosum/glia:2.44

pineal gland:3.78

peripheral nerve:-

spine:3.29

retina:-

eye:-

artery/aorta:1.33

vein:2.57

lymphnode:2.54

peripheral blood:-

spleen:1.50

thymus:2.46

bone marrow:-

adipose:1.41

bone:-

skin:-

RNA-seq

cerebrum:0.01

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.51

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.02

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:22.50

ovary:-

testis:8.70

heart:76.60

muscle:60.30

esophagus:-

stomach:-

intestine:-

colon:17

liver/hepato:10.60

lung:9.80

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:44.50

breast:-

salivary:-

GeneChip

uterus:4.89

placenta:4.90

prostate:4.74

ovary:5.03

testis:4.73

heart:5.05

muscle:6.74

esophagus:5.34

stomach:4.94

intestine:5.59

colon:5.23

liver/hepato:4.95

lung:4.94

bladder:-

kidney:4.67

pituitary:5.41

thyroid/parathyroid:4.66

adrenal gland:4.65

pancreas:5.25

breast:4.74

salivary:5.23

CAGE

uterus:1.69

placenta:0.88

prostate:1.86

ovary:1.68

testis:1.39

heart:1.30

muscle:3.47

esophagus:1.75

stomach:-

intestine:3.21

colon:2.39

liver/hepato:1.01

lung:1.51

bladder:1.24

kidney:0.98

pituitary:2.13

thyroid/parathyroid:1.30

adrenal gland:-

pancreas:0.94

breast:0.90

salivary:2.26

RNA-seq

uterus:-

placenta:-

prostate:0.10

ovary:0.25

testis:0.13

heart:0.00

muscle:2.45

esophagus:-

stomach:-

intestine:-

colon:0.10

liver/hepato:0.00

lung:1.07

bladder:-

kidney:0.01

pituitary:-

thyroid/parathyroid:1.07

adrenal gland:0.83

pancreas:-

breast:0.23

salivary:-

IDs

Refseq ID	NM_015831
Gene ID	43
Unigene ID	Hs.154495
Probe set ID	205377_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000087085
GTEx ID	ENSG00000087085

Orthologous Gene

Mouse[1]	NM_009599
Rat[1]	NM_009599

Chromosomal Region

7q22.1 [100,487,615 - 100,494,594]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000997

Cholinesterase

Gene Ontology (GO ID)

Biological Process

GO:0006581	acetylcholine catabolic process
GO:0001507	acetylcholine catabolic process in synaptic cleft
GO:0042982	amyloid precursor protein metabolic process
GO:0007155	cell adhesion
GO:0008283	cell proliferation
GO:0019695	choline metabolic process
GO:0006260	DNA replication
GO:0046474	glycerophospholipid biosynthetic process
GO:0007517	muscle organ development
GO:0032223	negative regulation of synaptic transmission, cholinergic
GO:0007399	nervous system development
GO:0042136	neurotransmitter biosynthetic process
GO:0045212	neurotransmitter receptor biosynthetic process
GO:0002076	osteoblast development
GO:0006656	phosphatidylcholine biosynthetic process
GO:0006644	phospholipid metabolic process
GO:0050714	positive regulation of protein secretion
GO:0051262	protein tetramerization
GO:0031623	receptor internalization
GO:0050770	regulation of axonogenesis
GO:0048814	regulation of dendrite morphogenesis
GO:0001919	regulation of receptor recycling
GO:0009611	response to wounding
GO:0060041	retina development in camera-type eye
GO:0007416	synapse assembly
GO:0007268	synaptic transmission
GO:0007271	synaptic transmission, cholinergic

Cellular Component

GO:0031225	anchored to membrane
GO:0030424	axon
GO:0005605	basal lamina
GO:0030054	cell junction
GO:0009986	cell surface
GO:0030425	dendrite
GO:0005788	endoplasmic reticulum lumen
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0031594	neuromuscular junction
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0042734	presynaptic membrane
GO:0045202	synapse

Molecular Function

GO:0042166	acetylcholine binding
GO:0003990	acetylcholinesterase activity
GO:0001540	beta-amyloid binding
GO:0004091	carboxylesterase activity
GO:0004104	cholinesterase activity
GO:0005518	collagen binding
GO:0016787	hydrolase activity
GO:0043236	laminin binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0043621	protein self-association
GO:0017171	serine hydrolase activity

acetylcholinesterase (Yt blood group)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function