aldehyde dehydrogenase 6 family, member A1

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Synonym

MGC40271, MMSDH, aldehyde dehydrogenase 6 family, member A1, MMSADHA, ALDH6A1, Malonate-semialdehyde dehydrogenase [acylating]

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:156.40 cerebellum:88.20 brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:60 vein:- lymphnode:10.10 peripheral blood:18.20 spleen:37.80 thymus:12.90 bone marrow:39.40 adipose:40.30 bone:25.60 skin:33.60
GeneChip cerebrum:8.51 cerebellum:8.02 brain stem:8.28 corpus callosum/glia:8.81 pineal gland:- peripheral nerve:7.75 spine:8.78 retina:- eye:- artery/aorta:6.98 vein:6.72 lymphnode:6.16 peripheral blood:- spleen:6.06 thymus:6.53 bone marrow:6.07 adipose:7.92 bone:- skin:6.49
CAGE cerebrum:4.58 cerebellum:- brain stem:4.52 corpus callosum/glia:4.85 pineal gland:3.39 peripheral nerve:- spine:4.55 retina:- eye:- artery/aorta:3.47 vein:3.50 lymphnode:2.61 peripheral blood:- spleen:2.58 thymus:2.74 bone marrow:- adipose:3.76 bone:- skin:-
RNA-seq cerebrum:5.53 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.59 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.77 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:21.90 prostate:67.60 ovary:37.30 testis:77.90 heart:51.10 muscle:20.10 esophagus:- stomach:42.50 intestine:162 colon:25.40     liver/hepato:73.90        lung:34.20    bladder:251.20 kidney:769.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:44.50 breast:27.90 salivary:328.40
GeneChip uterus:7.23 placenta:5.86 prostate:8.30 ovary:7.65 testis:7.71 heart:7.55 muscle:7.40 esophagus:7.01 stomach:7.41 intestine:7.12 colon:7 liver/hepato:9.88 lung:6.77 bladder:- kidney:10.46 pituitary:6.69 thyroid/parathyroid:7.53 adrenal gland:7.01 pancreas:7.32 breast:7.32 salivary:7.56
CAGE uterus:3.54 placenta:2.48 prostate:3.71 ovary:3.75 testis:3.87 heart:3.47 muscle:3.20 esophagus:3.50 stomach:- intestine:4.06 colon:3.89     liver/hepato:5.57    lung:3.31 bladder:3.74 kidney:4.78 pituitary:3.11 thyroid/parathyroid:3.82 adrenal gland:- pancreas:4.22 breast:3.24 salivary:3.96
RNA-seq uterus:- placenta:- prostate:4.03 ovary:3.69 testis:3.47 heart:4.27 muscle:3.94 esophagus:- stomach:- intestine:- colon:3.60     liver/hepato:5.65        lung:2.63    bladder:- kidney:5.08 pituitary:- thyroid/parathyroid:4.35 adrenal gland:2.16 pancreas:- breast:4.01 salivary:-

Gene Information

IDs

Refseq ID NM_005589
Gene ID 4329
Unigene ID Hs.293970
Probe set ID 204290_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000119711
GTEx ID ENSG00000119711

Orthologous Gene

Mouse[1]  NM_134042
Rat [0]  

Chromosomal Region

14q24.3  [74,523,553  -  74,551,196]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1527093
8125298
10947204
12477932
14718574
15489334
15909363
18029348
19343046
20379614
20585627
20877624
21863277
21988832
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0009083  branched chain family amino acid catabolic process
GO:0050873  brown fat cell differentiation
GO:0034641  cellular nitrogen compound metabolic process
GO:0019859  thymine metabolic process
GO:0006573  valine metabolic process

Cellular Component

GO:0005759  mitochondrial matrix
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0000062  acyl-CoA binding
GO:0018478  malonate-semialdehyde dehydrogenase (acetylating) activity
GO:0004491  methylmalonate-semialdehyde dehydrogenase (acylating) activity