v-myc myelocytomatosis viral oncogene homolog (avian)

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Synonym

Transcription factor p64, Myc proto-oncogene protein, MYC, c-Myc

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:52.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:- eye:17.60 artery/aorta:209.80 vein:- lymphnode:80.90 peripheral blood:200.40 spleen:37.80 thymus:103.10 bone marrow:19.70 adipose:121 bone:89.60 skin:81.60
GeneChip cerebrum:4.91 cerebellum:4.65 brain stem:5.22 corpus callosum/glia:4.88 pineal gland:- peripheral nerve:6.97 spine:6.26 retina:- eye:- artery/aorta:7.78 vein:8.84 lymphnode:7.08 peripheral blood:- spleen:7.18 thymus:7.40 bone marrow:7.81 adipose:8.46 bone:- skin:8.99
CAGE cerebrum:2.88 cerebellum:- brain stem:3.24 corpus callosum/glia:3.03 pineal gland:3.42 peripheral nerve:- spine:4.09 retina:- eye:- artery/aorta:4.72 vein:5.11 lymphnode:5.06 peripheral blood:- spleen:5.17 thymus:5.06 bone marrow:- adipose:5.78 bone:- skin:-
RNA-seq cerebrum:1.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.73 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.38 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:36.40 prostate:67.60 ovary:- testis:13 heart:12.80 muscle:20.10 esophagus:- stomach:85 intestine:97.20 colon:127.20     liver/hepato:21.10        lung:39.10    bladder:628.10 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:71.10 breast:74.30 salivary:328.40
GeneChip uterus:7.93 placenta:6.49 prostate:7.84 ovary:8.41 testis:6.36 heart:7.15 muscle:6.14 esophagus:8.13 stomach:7.32 intestine:7.46 colon:7.79 liver/hepato:5.83 lung:7.58 bladder:- kidney:5.47 pituitary:4.74 thyroid/parathyroid:6.16 adrenal gland:7.68 pancreas:8.16 breast:8.57 salivary:6.66
CAGE uterus:4.81 placenta:4.22 prostate:4.64 ovary:5.24 testis:4.50 heart:4.67 muscle:5.06 esophagus:5.41 stomach:- intestine:4.41 colon:4.58     liver/hepato:4.95    lung:4.11 bladder:4.95 kidney:3.95 pituitary:3.11 thyroid/parathyroid:3.75 adrenal gland:- pancreas:5.57 breast:5.14 salivary:4.13
RNA-seq uterus:- placenta:- prostate:4.19 ovary:4.93 testis:3.51 heart:2.60 muscle:5.81 esophagus:- stomach:- intestine:- colon:4.60     liver/hepato:3.27        lung:4.64    bladder:- kidney:3.12 pituitary:- thyroid/parathyroid:3.37 adrenal gland:5.62 pancreas:- breast:5.02 salivary:-

IDs

Refseq ID NM_002467
Gene ID 4609
Unigene ID Hs.202453
Probe set ID 202431_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000136997
GTEx ID ENSG00000136997

Orthologous Gene

Mouse[1]  NM_023326
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

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Link to Pubmed  (Pubmed ID)

1318011
1559612
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Gene Ontology  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0001783  B cell apoptosis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0007050  cell cycle arrest
GO:0006879  cellular iron ion homeostasis
GO:0034644  cellular response to UV
GO:0006338  chromatin remodeling
GO:0051276  chromosome organization
GO:0050910  detection of mechanical stimulus involved in sensory perception of sound
GO:0006309  DNA fragmentation involved in apoptosis
GO:0006112  energy reserve metabolic process
GO:0010467  gene expression
GO:0006006  glucose metabolic process
GO:0000165  MAPKKK cascade
GO:0042474  middle ear morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0051782  negative regulation of cell division
GO:0048147  negative regulation of fibroblast proliferation
GO:0045656  negative regulation of monocyte differentiation
GO:0032091  negative regulation of protein binding
GO:0032873  negative regulation of stress-activated MAPK cascade
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007219  Notch signaling pathway
GO:0015671  oxygen transport
GO:0043473  pigmentation
GO:0002904  positive regulation of B cell apoptosis
GO:0043280  positive regulation of caspase activity
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0048146  positive regulation of fibroblast proliferation
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0090096  positive regulation of metanephric cap mesenchymal cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0016485  protein processing
GO:0007346  regulation of mitotic cell cycle
GO:0032204  regulation of telomere maintenance
GO:0001836  release of cytochrome c from mitochondria
GO:0043279  response to alkaloid
GO:0006974  response to DNA damage stimulus
GO:0042493  response to drug
GO:0010332  response to gamma radiation
GO:0070848  response to growth factor stimulus
GO:0048705  skeletal system morphogenesis
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005819  spindle

Molecular Function

GO:0003677  DNA binding
GO:0003690  double-stranded DNA binding
GO:0070888  E-box binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046982  protein heterodimerization activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding