zinc finger homeobox 3

Synonym

ATBF1, AT motif binding factor 1 (ATBF1), AT motif-binding factor, ATBF1 (AT motif binding factor 1), Alpha-fetoprotein enhancer-binding protein, ATBT, AT-binding transcription factor 1, ZFHX3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.18

cerebellum:4.36

brain stem:5.12

corpus callosum/glia:5.20

pineal gland:-

peripheral nerve:6.47

spine:5.45

retina:-

eye:-

artery/aorta:6.66

vein:6.22

lymphnode:4.98

peripheral blood:-

spleen:5.16

thymus:4.35

bone marrow:4.47

adipose:5.80

bone:-

skin:5.13

CAGE

cerebrum:2.16

cerebellum:-

brain stem:2.17

corpus callosum/glia:2.66

pineal gland:3.32

peripheral nerve:-

spine:3.24

retina:-

eye:-

artery/aorta:3.95

vein:2.86

lymphnode:2.20

peripheral blood:-

spleen:2.71

thymus:1.43

bone marrow:-

adipose:2.79

bone:-

skin:-

RNA-seq

cerebrum:0.31

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.33

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.31

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.96

placenta:5.64

prostate:6.69

ovary:5.57

testis:4.76

heart:6.03

muscle:5.32

esophagus:5.48

stomach:5.83

intestine:5.37

colon:5.64

liver/hepato:5.70

lung:6

bladder:-

kidney:5.55

pituitary:6.39

thyroid/parathyroid:6.76

adrenal gland:6.45

pancreas:5.29

breast:5.68

salivary:5.66

CAGE

uterus:3.25

placenta:2.93

prostate:3.37

ovary:2.63

testis:2.71

heart:3.07

muscle:3.09

esophagus:2.58

stomach:-

intestine:2.54

colon:3.13

liver/hepato:2.66

lung:3.05

bladder:3.41

kidney:2.48

pituitary:3.29

thyroid/parathyroid:3.17

adrenal gland:-

pancreas:3.13

breast:3.30

salivary:2.75

RNA-seq

uterus:-

placenta:-

prostate:0.61

ovary:0.51

testis:0.72

heart:0.61

muscle:1.23

esophagus:-

stomach:-

intestine:-

colon:0.90

liver/hepato:0.17

lung:0.50

bladder:-

kidney:0.52

pituitary:-

thyroid/parathyroid:1.51

adrenal gland:0.68

pancreas:-

breast:0.91

salivary:-

IDs

Refseq ID	NM_006885
Gene ID	463
Unigene ID	Hs.598297
Probe set ID	208033_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140836
GTEx ID	ENSG00000140836

Orthologous Gene

Mouse[6]	NM_007496
Rat[6]	NM_007496

Chromosomal Region

16q22.3 [72,816,784 - 73,092,534]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related
IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type
IPR003604	Zinc finger, U1-type

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007517	muscle organ development
GO:0045662	negative regulation of myoblast differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045663	positive regulation of myoblast differentiation
GO:0006355	regulation of transcription, DNA-dependent
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0044212	DNA regulatory region binding
GO:0019899	enzyme binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008270	zinc ion binding

zinc finger homeobox 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function