NGFI-A binding protein 2 (EGR1 binding protein 2)

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Synonym

MGC75085, NGFI-A binding protein 2 (EGR1 binding protein 2), NAB2, Melanoma-associated delayed early response protein, MADER, Protein MADER, NGFI-A-binding protein 2, EGR-1-binding protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:40.30 cerebellum:50.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:35.30 artery/aorta:- vein:- lymphnode:30.30 peripheral blood:18.20 spleen:56.70 thymus:64.40 bone marrow:- adipose:40.30 bone:25.60 skin:24
GeneChip cerebrum:4.86 cerebellum:5.59 brain stem:4.78 corpus callosum/glia:4.68 pineal gland:- peripheral nerve:4.96 spine:4.73 retina:- eye:- artery/aorta:5.07 vein:5.19 lymphnode:4.80 peripheral blood:- spleen:4.58 thymus:5.07 bone marrow:4.93 adipose:5.10 bone:- skin:5.12
CAGE cerebrum:2.33 cerebellum:- brain stem:1.78 corpus callosum/glia:1.83 pineal gland:2.87 peripheral nerve:- spine:1.67 retina:- eye:- artery/aorta:2.92 vein:2.35 lymphnode:1.51 peripheral blood:- spleen:1.99 thymus:2.40 bone marrow:- adipose:2.41 bone:- skin:-
RNA-seq cerebrum:2.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.23 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.27 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:14.60 prostate:78.90 ovary:111.80 testis:17.30 heart:25.50 muscle:20.10 esophagus:- stomach:- intestine:- colon:-     liver/hepato:10.60        lung:39.10    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:18.60 salivary:-
GeneChip uterus:5.10 placenta:4.77 prostate:4.80 ovary:5.23 testis:4.71 heart:5 muscle:4.94 esophagus:5.18 stomach:4.77 intestine:4.85 colon:5 liver/hepato:4.73 lung:4.87 bladder:- kidney:4.81 pituitary:5.11 thyroid/parathyroid:4.69 adrenal gland:4.96 pancreas:5.31 breast:4.81 salivary:5.14
CAGE uterus:3.14 placenta:2.59 prostate:2.79 ovary:3.05 testis:2.41 heart:2.22 muscle:1.48 esophagus:2.45 stomach:- intestine:1.79 colon:2.15     liver/hepato:1.71    lung:2.07 bladder:2.73 kidney:1.64 pituitary:2.36 thyroid/parathyroid:2.25 adrenal gland:- pancreas:1.42 breast:2.19 salivary:1.67
RNA-seq uterus:- placenta:- prostate:4.18 ovary:4.43 testis:3.68 heart:1.41 muscle:2.12 esophagus:- stomach:- intestine:- colon:3.30     liver/hepato:1.78        lung:3.69    bladder:- kidney:2.43 pituitary:- thyroid/parathyroid:4.17 adrenal gland:2.69 pancreas:- breast:2.33 salivary:-

Gene Information

IDs

Refseq ID NM_005967
Gene ID 4665
Unigene ID Hs.159223
Probe set ID 216017_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166886
GTEx ID ENSG00000166886

Orthologous Gene

Mouse[4]  NM_001122895, NM_008668
Rat[1]  NM_001134874, NM_008668

Chromosomal Region

12q13.3  [57,482,677  -  57,489,259]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8649813
8668170
9126479
9722618
9774344
11135623
11567222
12030330
12427750
12477932
15489334
16260776
16344560
16574654
17081983
19423540
19460752
19471022
19888474
19913121
20237496
20406964
20438785
20506119
20628086
21693764
21836637
22075330
22431919
22939629
23313952
23313954
23416169
23575898
23761323
23817571
23834954

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0001958  endochondral ossification
GO:0042552  myelination
GO:0016480  negative regulation of transcription from RNA polymerase III promoter
GO:0007399  nervous system development
GO:0045682  regulation of epidermis development
GO:0014037  Schwann cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding