NCK adaptor protein 1

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Synonym

SH2/SH3 adaptor protein NCK-alpha, MGC12668, NCK1, Cytoplasmic protein NCK1, NCK adaptor protein 1, NCKalpha, NCK

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:37.90

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:148.30

peripheral nerve:61.30

spine:112.30

retina:-

eye:-

artery/aorta:-

vein:266.60

lymphnode:121.30

peripheral blood:-

spleen:37.80

thymus:206.10

bone marrow:19.70

adipose:161.30

bone:38.40

skin:67.20

GeneChip

cerebrum:5.50

cerebellum:5.79

brain stem:5.94

corpus callosum/glia:5.48

pineal gland:-

peripheral nerve:6.18

spine:5.77

retina:-

eye:-

artery/aorta:6.25

vein:6.36

lymphnode:6.87

peripheral blood:-

spleen:6.50

thymus:8.08

bone marrow:5.94

adipose:7.02

bone:-

skin:6.92

CAGE

cerebrum:3.31

cerebellum:-

brain stem:3.29

corpus callosum/glia:2.92

pineal gland:3.50

peripheral nerve:-

spine:3.55

retina:-

eye:-

artery/aorta:3.68

vein:3.96

lymphnode:4.02

peripheral blood:-

spleen:3.62

thymus:4.24

bone marrow:-

adipose:4.54

bone:-

skin:-

RNA-seq

cerebrum:2.84

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.05

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.80

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:47.40

prostate:33.80

ovary:-

testis:60.60

heart:25.50

muscle:20.10

esophagus:-

stomach:-

intestine:64.80

colon:33.90

liver/hepato:21.10

lung:48.90

bladder:-

kidney:93.60

pituitary:116

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:35.60

breast:55.80

salivary:-

GeneChip

uterus:6.77

placenta:6.53

prostate:6.91

ovary:6.59

testis:6.34

heart:6.32

muscle:6.52

esophagus:6.89

stomach:6.12

intestine:6.17

colon:5.36

liver/hepato:5.94

lung:6.39

bladder:-

kidney:5.19

pituitary:5.81

thyroid/parathyroid:6.41

adrenal gland:5.93

pancreas:5.33

breast:6.75

salivary:5.87

CAGE

uterus:3.89

placenta:3.76

prostate:4.04

ovary:3.69

testis:3.60

heart:3.72

muscle:3.93

esophagus:4.22

stomach:-

intestine:3.10

colon:3.49

liver/hepato:3.46

lung:4.04

bladder:4.02

kidney:3.34

pituitary:3.82

thyroid/parathyroid:3.82

adrenal gland:-

pancreas:3.32

breast:4.39

salivary:3.40

RNA-seq

uterus:-

placenta:-

prostate:4.17

ovary:4.14

testis:3.95

heart:2.40

muscle:3.20

esophagus:-

stomach:-

intestine:-

colon:3.79

liver/hepato:2.64

lung:4.18

bladder:-

kidney:3.10

pituitary:-

thyroid/parathyroid:3.87

adrenal gland:3.60

pancreas:-

breast:3.49

salivary:-

IDs

Refseq ID	NM_006153
Gene ID	4690
Unigene ID	Hs.477693
Probe set ID	211063_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000158092
GTEx ID	ENSG00000158092

Orthologous Gene

Mouse[4]	NM_010878
Rat [0]

Chromosomal Region

3q22.3 [136,581,050 - 136,668,665]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007015	actin filament organization
GO:0007411	axon guidance
GO:0016477	cell migration
GO:0045087	innate immune response
GO:0030032	lamellipodium assembly
GO:0060548	negative regulation of cell death
GO:0006469	negative regulation of protein kinase activity
GO:0030838	positive regulation of actin filament polymerization
GO:0042102	positive regulation of T cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006417	regulation of translation
GO:0051707	response to other organism
GO:0007172	signal complex assembly
GO:0042110	T cell activation
GO:0050852	T cell receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0012506	vesicle membrane

Molecular Function

GO:0008093	cytoskeletal adaptor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0004860	protein kinase inhibitor activity
GO:0005102	receptor binding
GO:0030159	receptor signaling complex scaffold activity

NCK adaptor protein 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function