neurofilament, medium polypeptide

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Synonym

Neurofilament triplet M protein, Neurofilament medium polypeptide, neurofilament 3 (150kD medium), NEFM, NF-M, NEF3, neurofilament 3 (150kDa medium), 160 kDa neurofilament protein, NFM, Neurofilament 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:111.40 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:148.30 peripheral nerve:276 spine:786.10 retina:- eye:76.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:10.03 cerebellum:8.53 brain stem:11.04 corpus callosum/glia:5.59 pineal gland:- peripheral nerve:13.06 spine:10.37 retina:- eye:- artery/aorta:4.15 vein:4.28 lymphnode:4.32 peripheral blood:- spleen:3.89 thymus:4.23 bone marrow:3.85 adipose:4.10 bone:- skin:4.37
CAGE cerebrum:5.65 cerebellum:- brain stem:5.58 corpus callosum/glia:4.38 pineal gland:6.10 peripheral nerve:- spine:5.38 retina:- eye:- artery/aorta:0.69 vein:1.69 lymphnode:0.66 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:6.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.33 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:17.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.67 placenta:3.87 prostate:5.02 ovary:4.44 testis:6.82 heart:4.10 muscle:4.07 esophagus:4.71 stomach:3.96 intestine:4.14 colon:4.13 liver/hepato:3.98 lung:3.97 bladder:- kidney:4.20 pituitary:6.95 thyroid/parathyroid:4.01 adrenal gland:6.26 pancreas:4.36 breast:4.12 salivary:4.03
CAGE uterus:2.30 placenta:0.08 prostate:1.38 ovary:0.95 testis:2.21 heart:0.83 muscle:0.62 esophagus:0.52 stomach:- intestine:0.61 colon:0.51     liver/hepato:0    lung:0 bladder:1.62 kidney:1.09 pituitary:2.90 thyroid/parathyroid:0.06 adrenal gland:- pancreas:1.59 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.99 ovary:0.97 testis:1.90 heart:0.01 muscle:0.07 esophagus:- stomach:- intestine:- colon:0.84     liver/hepato:0.00        lung:0.22    bladder:- kidney:0.59 pituitary:- thyroid/parathyroid:0.47 adrenal gland:0.01 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_005382
Gene ID 4741
Unigene ID Hs.458657
Probe set ID 205113_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104722
GTEx ID ENSG00000104722

Orthologous Gene

Mouse[2]  NM_008691
Rat [0]  

Chromosomal Region

8p21.2  [24,770,525  -  24,776,607]

Gene Family (Interpro ID)

IPR001664  Intermediate filament protein
IPR002957  Keratin, type I

Link to Pubmed  (Pubmed ID)

1348579
1537832
2450354
2557834
3608989
7790359
7829101
8344946
8620924
8702840
10762698
11563628
12133495
12477932
12963086
14583397
14662745
15032605
15290901
15342556
15822905
16006557
16084104
16734940
17043677
17498690
18029348
19034380
20195357
20201926
20213320
20381070
20471030
20562859
20624930
21139048
21219885
21565611
21816823
21890473
21956116
22586326
24244333
24250222
24636402

Gene Ontology  (GO ID)

Biological Process

GO:0008088  axon cargo transport
GO:0045110  intermediate filament bundle assembly
GO:0000226  microtubule cytoskeleton organization
GO:0060052  neurofilament cytoskeleton organization
GO:0031133  regulation of axon diameter

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0005883  neurofilament
GO:0031594  neuromuscular junction

Molecular Function

GO:0005515  protein binding
GO:0005200  structural constituent of cytoskeleton