neurogenic differentiation 2

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Synonym

Neurogenic differentiation factor 2, MGC26304, NEUROD2, neurogenic differentiation 2, NeuroD2, NeuroD-related factor, NDRF

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.50 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.50 cerebellum:6.75 brain stem:5.35 corpus callosum/glia:5 pineal gland:- peripheral nerve:4.82 spine:5.07 retina:- eye:- artery/aorta:4.88 vein:4.94 lymphnode:4.85 peripheral blood:- spleen:4.74 thymus:4.83 bone marrow:5 adipose:4.91 bone:- skin:5.08
CAGE cerebrum:3.09 cerebellum:- brain stem:1.99 corpus callosum/glia:1.58 pineal gland:2.83 peripheral nerve:- spine:0.92 retina:- eye:- artery/aorta:0.69 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:2.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.71 placenta:4.53 prostate:4.59 ovary:4.67 testis:4.71 heart:4.62 muscle:4.83 esophagus:4.74 stomach:4.66 intestine:4.73 colon:4.72 liver/hepato:4.76 lung:4.72 bladder:- kidney:4.53 pituitary:5.05 thyroid/parathyroid:4.81 adrenal gland:4.74 pancreas:5.29 breast:4.68 salivary:4.49
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.21 heart:0.03 muscle:0 esophagus:0.09 stomach:- intestine:0.21 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.03 ovary:0.01 testis:0.05 heart:0 muscle:0.02 esophagus:- stomach:- intestine:- colon:0.01     liver/hepato:0        lung:0    bladder:- kidney:0.04 pituitary:- thyroid/parathyroid:0 adrenal gland:0.01 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_006160
Gene ID 4761
Unigene ID Hs.322431
Probe set ID 210271_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171532
GTEx ID ENSG00000171532

Orthologous Gene

Mouse[1]  NM_010895
Rat[1]  NM_010895

Chromosomal Region

17q12  [37,760,021  -  37,764,196]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8816493
9119405
9748526
10209266
10640683
10662545
11473083
11732772
11900979
12477932
14732494
15489334
16607387
17117180
19086053
19124506
20880594
21900206
22752091

Gene Ontology  (GO ID)

Biological Process

GO:0008306  associative learning
GO:0001662  behavioral fear response
GO:0071277  cellular response to calcium ion
GO:0071257  cellular response to electrical stimulus
GO:0021695  cerebellar cortex development
GO:0007399  nervous system development
GO:0048666  neuron development
GO:0050850  positive regulation of calcium-mediated signaling
GO:0045666  positive regulation of neuron differentiation
GO:0090129  positive regulation of synapse maturation
GO:0031915  positive regulation of synaptic plasticity
GO:0051091  positive regulation of transcription factor activity
GO:0016567  protein ubiquitination
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0070888  E-box binding
GO:0046982  protein heterodimerization activity
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity