nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Synonym

NFATc, NF-ATC, MGC138448, NFAT2, NF-ATc, NF-ATc1, Nuclear factor of activated T-cells, cytoplasmic 1, NFATC, NFATC1, NFAT transcription complex cytosolic component

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:9.50

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:66.60

lymphnode:161.80

peripheral blood:36.40

spleen:113.40

thymus:38.70

bone marrow:19.70

adipose:40.30

bone:38.40

skin:4.80

GeneChip

cerebrum:6.42

cerebellum:6.52

brain stem:6.54

corpus callosum/glia:6.35

pineal gland:-

peripheral nerve:6.01

spine:6.17

retina:-

eye:-

artery/aorta:6.30

vein:6.67

lymphnode:6.21

peripheral blood:-

spleen:6.06

thymus:5.76

bone marrow:6.57

adipose:6.41

bone:-

skin:6.41

CAGE

cerebrum:1.96

cerebellum:-

brain stem:2.13

corpus callosum/glia:2.62

pineal gland:1.77

peripheral nerve:-

spine:2.62

retina:-

eye:-

artery/aorta:4.13

vein:4.09

lymphnode:3.94

peripheral blood:-

spleen:3.60

thymus:3.66

bone marrow:-

adipose:3.35

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:7.30

prostate:56.30

ovary:111.80

testis:51.90

heart:153.30

muscle:20.10

esophagus:-

stomach:21.20

intestine:-

colon:59.40

liver/hepato:-

lung:92.90

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:18.60

salivary:-

GeneChip

uterus:6.18

placenta:6.30

prostate:5.75

ovary:6.33

testis:6.19

heart:6.59

muscle:6.91

esophagus:6.14

stomach:6.24

intestine:6.50

colon:6.58

liver/hepato:6.34

lung:6.25

bladder:-

kidney:6.40

pituitary:6.26

thyroid/parathyroid:6.09

adrenal gland:6.34

pancreas:6.74

breast:6.08

salivary:6.35

CAGE

uterus:3.21

placenta:2.04

prostate:2.78

ovary:2.84

testis:2.85

heart:3.39

muscle:3.72

esophagus:2.68

stomach:-

intestine:2.16

colon:2.68

liver/hepato:1.57

lung:3.56

bladder:3.40

kidney:1.91

pituitary:1.60

thyroid/parathyroid:2.43

adrenal gland:-

pancreas:2.34

breast:2.95

salivary:2.01

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.00

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_006162
Gene ID	4772
Unigene ID	Hs.534074
Probe set ID	208196_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000131196
GTEx ID	ENSG00000131196

Orthologous Gene

Mouse[8]	NM_001164109, NM_001164110, NM_001164111, NM_001164112, NM_016791, NM_198429
Rat[8]	NM_001164109, NM_001164110, NM_001164111, NM_001164112, NM_016791, NM_198429

Chromosomal Region

18q23 [77,155,772 - 77,289,325]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002909	Cell surface receptor IPT/TIG
IPR014756	Immunoglobulin E-set
IPR008366	Nuclear factor of activated T cells (NFAT)
IPR008967	p53-like transcription factor, DNA-binding
IPR011539	Rel homology

Gene Ontology (GO ID)

Biological Process

GO:0006816	calcium ion transport
GO:0001837	epithelial to mesenchymal transition
GO:0000082	G1/S transition of mitotic cell cycle
GO:0007507	heart development
GO:0045087	innate immune response
GO:0030316	osteoclast differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0000790	nuclear chromatin
GO:0005654	nucleoplasm
GO:0005667	transcription factor complex

Molecular Function

GO:0044212	DNA regulatory region binding
GO:0005528	FK506 binding
GO:0048273	mitogen-activated protein kinase p38 binding
GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0003700	transcription factor activity

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function