ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

Synonym

Endoplasmic reticulum class 1/2 Ca(2+) ATPase, DAR, ATP2B, DD, SR Ca(2+)-ATPase 2, SERCA2, ATP2A2, Calcium pump 2, MGC45367

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:219.30

cerebellum:214.10

brain stem:-

corpus callosum/glia:204.10

pineal gland:-

peripheral nerve:429.40

spine:112.30

retina:474.60

eye:311.50

artery/aorta:60

vein:-

lymphnode:151.70

peripheral blood:18.20

spleen:37.80

thymus:90.20

bone marrow:78.70

adipose:242

bone:102.40

skin:331.20

GeneChip

cerebrum:10.05

cerebellum:10.13

brain stem:9.52

corpus callosum/glia:8.73

pineal gland:-

peripheral nerve:8.91

spine:8.86

retina:-

eye:-

artery/aorta:8.95

vein:10.53

lymphnode:7.23

peripheral blood:-

spleen:7.48

thymus:7.35

bone marrow:5.95

adipose:7.98

bone:-

skin:8.69

CAGE

cerebrum:5.25

cerebellum:-

brain stem:4.83

corpus callosum/glia:4.86

pineal gland:4.73

peripheral nerve:-

spine:4.82

retina:-

eye:-

artery/aorta:5.46

vein:4.72

lymphnode:4.88

peripheral blood:-

spleen:4.48

thymus:3.92

bone marrow:-

adipose:4.53

bone:-

skin:-

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:191.40

placenta:83.80

prostate:180.20

ovary:186.30

testis:225

heart:562

muscle:2672

esophagus:342.80

stomach:212.40

intestine:64.80

colon:118.70

liver/hepato:147.80

lung:229.70

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:152.40

pancreas:142.30

breast:269.50

salivary:-

GeneChip

uterus:8.47

placenta:7.45

prostate:8.97

ovary:8.61

testis:8.01

heart:11.45

muscle:13

esophagus:10.35

stomach:7.98

intestine:8.78

colon:7.94

liver/hepato:8.12

lung:7.84

bladder:-

kidney:7.94

pituitary:7.83

thyroid/parathyroid:8.24

adrenal gland:8.48

pancreas:6.46

breast:8.37

salivary:8.20

CAGE

uterus:4.58

placenta:4.11

prostate:4.89

ovary:4.46

testis:4.79

heart:7.17

muscle:7.00

esophagus:5.36

stomach:-

intestine:4.83

colon:4.89

liver/hepato:5.01

lung:4.74

bladder:5.07

kidney:4.63

pituitary:4.39

thyroid/parathyroid:5.17

adrenal gland:-

pancreas:4.47

breast:4.71

salivary:5.37

RNA-seq

nodata

IDs

Refseq ID	NM_001135765
Gene ID	488
Unigene ID	Hs.506759
Probe set ID	212361_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000174437
GTEx ID	ENSG00000174437

Orthologous Gene

Mouse[6]	NM_001110140, NM_009722
Rat[3]	NM_001110139, NM_001110823

Chromosomal Region

12q24.11 [110,718,561 - 110,788,898]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006069	ATPase, P-type cation exchange, alpha subunit
IPR005782	ATPase, P-type, calcium-transporting
IPR000695	ATPase, P-type, H+ transporting proton pump
IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter

Gene Ontology (GO ID)

Biological Process

GO:0007596	blood coagulation
GO:0007155	cell adhesion
GO:0006874	cellular calcium ion homeostasis
GO:0008544	epidermis development
GO:0006984	ER-nuclear signaling pathway
GO:0034220	ion transmembrane transport
GO:0045822	negative regulation of heart contraction
GO:0010460	positive regulation of heart rate
GO:0002026	regulation of the force of heart contraction
GO:0055119	relaxation of cardiac muscle
GO:0070296	sarcoplasmic reticulum calcium ion transport
GO:0055085	transmembrane transport
GO:0006810	transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005887	integral to plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0016020	membrane
GO:0031095	platelet dense tubular network membrane
GO:0016529	sarcoplasmic reticulum
GO:0033017	sarcoplasmic reticulum membrane

Molecular Function

GO:0005524	ATP binding
GO:0005388	calcium-transporting ATPase activity
GO:0019899	enzyme binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding