neuropeptide Y receptor Y5

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Synonym

NPYY5, NPYR5, Neuropeptide Y receptor type 5, NPY5R, NPY-Y5 receptor, Y5 receptor, neuropeptide Y receptor Y5, NPY5-R

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.76 cerebellum:4.41 brain stem:4.71 corpus callosum/glia:4.46 pineal gland:- peripheral nerve:4.68 spine:4.77 retina:- eye:- artery/aorta:4.86 vein:4.92 lymphnode:4.57 peripheral blood:- spleen:5.18 thymus:4.12 bone marrow:4.56 adipose:5.23 bone:- skin:4.76
CAGE cerebrum:1.10 cerebellum:- brain stem:0.54 corpus callosum/glia:0.24 pineal gland:0 peripheral nerve:- spine:1.25 retina:- eye:- artery/aorta:1.79 vein:1.17 lymphnode:0.80 peripheral blood:- spleen:1.76 thymus:0 bone marrow:- adipose:1.76 bone:- skin:-
RNA-seq cerebrum:0.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.48 placenta:4.65 prostate:4.37 ovary:4.48 testis:5.23 heart:4.57 muscle:4.71 esophagus:4.42 stomach:4.59 intestine:4.53 colon:4.75 liver/hepato:4.55 lung:4.30 bladder:- kidney:4.70 pituitary:4.50 thyroid/parathyroid:4.45 adrenal gland:5.04 pancreas:4.67 breast:4.68 salivary:4.69
CAGE uterus:0.78 placenta:0.59 prostate:0.27 ovary:0.07 testis:1.43 heart:0.40 muscle:0.05 esophagus:0.33 stomach:- intestine:0 colon:0.39     liver/hepato:0.26    lung:0.40 bladder:0.26 kidney:1.14 pituitary:0.10 thyroid/parathyroid:0.17 adrenal gland:- pancreas:0 breast:1.16 salivary:0.83
RNA-seq uterus:- placenta:- prostate:0.22 ovary:0.15 testis:2.01 heart:0.12 muscle:0 esophagus:- stomach:- intestine:- colon:0.44     liver/hepato:0.09        lung:0.07    bladder:- kidney:1.35 pituitary:- thyroid/parathyroid:0.25 adrenal gland:1.19 pancreas:- breast:2.92 salivary:-

Gene Information

IDs

Refseq ID NM_006174
Gene ID 4889
Unigene ID Hs.598503
Probe set ID 207400_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164129
GTEx ID ENSG00000164129

Orthologous Gene

Mouse[2]  NM_016708
Rat [0]  

Chromosomal Region

4q32.2  [164,265,091  -  164,273,086]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR000611  Neuropeptide Y receptor
IPR000393  Neuropeptide Y5 receptor

Link to Pubmed  (Pubmed ID)

2834384
8700207
8824284
9169127
9417917
10575027
12007534
12220433
12398768
12477932
12665544
15302312
15601626
16891622
17325259
17426313
17948870
18577758
18828811
19058789
19077438
19086053
19481128
19593212
19759915
19874574
20332211
20468064
20602615
20797317
21988832
23932937

Gene Ontology  (GO ID)

Biological Process

GO:0003214  cardiac left ventricle morphogenesis
GO:0042755  eating behavior
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0060112  generation of ovulation cycle rhythm
GO:0014050  negative regulation of glutamate secretion
GO:0032229  negative regulation of synaptic transmission, GABAergic
GO:0003151  outflow tract morphogenesis
GO:0002675  positive regulation of acute inflammatory response
GO:0048661  positive regulation of smooth muscle cell proliferation

Cellular Component

GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004983  neuropeptide Y receptor activity
GO:0001602  pancreatic polypeptide receptor activity
GO:0001601  peptide YY receptor activity