WEE1 homolog 2 (S. pombe)

 jump to detail

Synonym

WEE2, WEE1B, FLJ16107, WEE1 homolog 2 (S. pombe), Wee1B kinase, Wee1-like protein kinase 1B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE nodata
RNA-seq cerebrum:0.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE nodata
RNA-seq uterus:- placenta:- prostate:0.03 ovary:0.06 testis:0.06 heart:0.02 muscle:0 esophagus:- stomach:- intestine:- colon:0.02     liver/hepato:0        lung:0.07    bladder:- kidney:0.04 pituitary:- thyroid/parathyroid:0.03 adrenal gland:0.04 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_001105558
Gene ID 494551
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000214102
GTEx ID ENSG00000214102

Orthologous Gene

Mouse[1]  NM_201370
Rat[1]  NM_201370

Chromosomal Region

7q34  [141,408,153  -  141,431,071]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

11029659
11181995
14702039
16341674
18029348
22623531
23568457

Gene Ontology  (GO ID)

Biological Process

GO:0007143  female meiosis
GO:0035038  female pronucleus formation
GO:0007067  mitosis
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0060631  regulation of meiosis I

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0000287  magnesium ion binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0004674  protein serine/threonine kinase activity