solute carrier family 22, member 18

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Synonym

IMPT1, Tumor-suppressing STF cDNA 5 protein, TSSC5, SLC22A1L, Solute carrier family 22 member 1-like, HET, Efflux transporter-like protein, SLC22A18, ORCTL2, BWSCR1A, p45-BWR1A, BWR1A, DKFZp667A184, p45-Beckwith-Wiedemann region 1 A, Solute carrier family 22 member 18, ITM, Organic cation transporter-like protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:14.40
GeneChip cerebrum:5.96 cerebellum:5.47 brain stem:5.94 corpus callosum/glia:5.71 pineal gland:- peripheral nerve:7.42 spine:6.07 retina:- eye:- artery/aorta:6.81 vein:6.64 lymphnode:6.70 peripheral blood:- spleen:6.39 thymus:6.20 bone marrow:6.39 adipose:6.81 bone:- skin:7.12
CAGE cerebrum:1.15 cerebellum:- brain stem:1.30 corpus callosum/glia:1.27 pineal gland:1.44 peripheral nerve:- spine:1.46 retina:- eye:- artery/aorta:2.56 vein:2.49 lymphnode:2.83 peripheral blood:- spleen:2.25 thymus:2.02 bone marrow:- adipose:2.31 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:37.30 testis:13 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:93.30     liver/hepato:10.60        lung:9.80    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:88.90 breast:46.50 salivary:-
GeneChip uterus:6.38 placenta:6.53 prostate:6.94 ovary:6.55 testis:7.58 heart:7.09 muscle:5.83 esophagus:7.14 stomach:6.81 intestine:7.30 colon:8.42 liver/hepato:8.79 lung:6.59 bladder:- kidney:9.01 pituitary:6.24 thyroid/parathyroid:7.61 adrenal gland:6.17 pancreas:6.71 breast:7.22 salivary:7.48
CAGE uterus:2.07 placenta:2.40 prostate:2.20 ovary:2.09 testis:2.18 heart:2.20 muscle:1.32 esophagus:2.73 stomach:- intestine:5.10 colon:4.55     liver/hepato:4.47    lung:2.90 bladder:2.30 kidney:3.74 pituitary:1.13 thyroid/parathyroid:2.96 adrenal gland:- pancreas:1.42 breast:1.92 salivary:3.22
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.15 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:1.72 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_183233
Gene ID 5002
Unigene ID Hs.50868
Probe set ID 204981_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000110628
GTEx ID ENSG00000110628

Orthologous Gene

Mouse[4]  NM_001042760, NM_008767
Rat[1]  NM_001004260, NM_008767

Chromosomal Region

11p15.4  [2,920,951  -  2,946,476]

Gene Family (Interpro ID)

IPR020846  Major facilitator superfamily
IPR011701  Major facilitator superfamily MFS-1
IPR016196  Major facilitator superfamily, general substrate transporter
IPR001958  Tetracycline resistance protein, TetA

Link to Pubmed  (Pubmed ID)

9499412
9520460
9570947
9744804
9751628
9802569
11076855
11925925
12477932
15342556
15489334
16314844
16344560
16624517
18996451
19414484
19946888
20201924
20301425
20705733
21144813
21890473
21906983
21936894
21963094
22153794
22237119
23514245

Gene Ontology  (GO ID)

Biological Process

GO:0015893  drug transport
GO:0007588  excretion
GO:0006855  multidrug transport
GO:0015695  organic cation transport
GO:0055085  transmembrane transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0044444  cytoplasmic part
GO:0016021  integral to membrane
GO:0005635  nuclear envelope
GO:0005886  plasma membrane

Molecular Function

GO:0015238  drug transporter activity
GO:0015293  symporter activity
GO:0031625  ubiquitin protein ligase binding