oxytocin, prepropeptide

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Synonym

oxytocin, prepro- (neurophysin I), Oxytocin-neurophysin 1 precursor, MGC126892, MGC126890, OXT, OT-NPI, OT

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.96 cerebellum:5.01 brain stem:4.92 corpus callosum/glia:4.72 pineal gland:- peripheral nerve:4.71 spine:4.72 retina:- eye:- artery/aorta:5.03 vein:5.28 lymphnode:4.69 peripheral blood:- spleen:4.46 thymus:4.50 bone marrow:4.97 adipose:5.01 bone:- skin:5.04
CAGE cerebrum:0.06 cerebellum:- brain stem:0 corpus callosum/glia:0.13 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:1.33 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.12 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.33 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.79 placenta:4.79 prostate:4.63 ovary:4.77 testis:5.03 heart:4.88 muscle:5.14 esophagus:4.82 stomach:4.75 intestine:5.12 colon:4.96 liver/hepato:5.15 lung:4.77 bladder:- kidney:5.05 pituitary:4.98 thyroid/parathyroid:4.51 adrenal gland:4.70 pancreas:5.33 breast:4.65 salivary:5.12
CAGE uterus:0 placenta:0.24 prostate:0 ovary:0.07 testis:0.55 heart:0.07 muscle:0 esophagus:0 stomach:- intestine:1.97 colon:0.32     liver/hepato:2.48    lung:0.05 bladder:0 kidney:0.54 pituitary:0.50 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.24 ovary:0 testis:1.40 heart:0.05 muscle:0 esophagus:- stomach:- intestine:- colon:0.29     liver/hepato:1.99        lung:0.14    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.32 adrenal gland:0.23 pancreas:- breast:1.49 salivary:-

Gene Information

IDs

Refseq ID NM_000915
Gene ID 5020
Unigene ID Hs.113216
Probe set ID 207576_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000101405
GTEx ID ENSG00000101405

Orthologous Gene

Mouse[1]  NM_011025
Rat [0]  

Chromosomal Region

20p13  [3,052,266  -  3,053,163]

Gene Family (Interpro ID)

IPR000981  Neurohypophysial hormone

Link to Pubmed  (Pubmed ID)

12173
1486803
2249637
2991279
3008332
3768139
4065330
6153132
6574452
7262323
9501254
9665335
10218979
10698266
10829090
11140838
11780052
12126740
12183418
12475731
12477932
12712516
12832367
12834028
12843193
13591312
14607844
15089975
15093695
15489334
16678285
16754659
16778082
17137561
17252002
17474147
17492653
17931766
18008328
18207134
18384894
18461271
18566739
18568974
18794210
18940936
19001515
19005082
19058789
19086053
19335381
19336370
19347709
19473710
19481007
19500216
19587265
19598235
19672816
19874574
19943975
20144509
20196918
20220015
20308198
20371820
20399783
20436377
20468064
20547007
20547038
20595062
20602615
20711752
21073007
21090345
21315262
21562482
21682649
21741363
21744319
21832819
21893160
21903023
21960250
21984889
22069312
22227278
22245314
22285934
22297159
22306668
22336563
22418012
22543270
22807189
22872688
22920910
22997507
23025690
23144787
23146328
23258269
23284856
23410756
23453164
23550008
23589638
23637833
23799864
23835346
23856187
23937196
23941164
24722188

Gene Ontology  (GO ID)

Biological Process

GO:0042756  drinking behavior
GO:0042755  eating behavior
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007565  female pregnancy
GO:0007625  grooming behavior
GO:0007507  heart development
GO:0042538  hyperosmotic salinity response
GO:0060179  male mating behavior
GO:0002125  maternal aggressive behavior
GO:0042711  maternal behavior
GO:0007613  memory
GO:0045776  negative regulation of blood pressure
GO:0060455  negative regulation of gastric acid secretion
GO:0045777  positive regulation of blood pressure
GO:0045925  positive regulation of female receptivity
GO:0060450  positive regulation of hindgut contraction
GO:0010701  positive regulation of norepinephrine secretion
GO:0045778  positive regulation of ossification
GO:0060406  positive regulation of penile erection
GO:0032308  positive regulation of prostaglandin secretion
GO:0050806  positive regulation of synaptic transmission
GO:0051965  positive regulation of synaptogenesis
GO:0070474  positive regulation of uterine smooth muscle contraction
GO:0002027  regulation of heart rate
GO:0051930  regulation of sensory perception of pain
GO:0014823  response to activity
GO:0001975  response to amphetamine
GO:0051591  response to cAMP
GO:0042220  response to cocaine
GO:0051602  response to electrical stimulus
GO:0032355  response to estradiol stimulus
GO:0045472  response to ether
GO:0051384  response to glucocorticoid stimulus
GO:0043434  response to peptide hormone stimulus
GO:0032570  response to progesterone stimulus
GO:0034695  response to prostaglandin E stimulus
GO:0032526  response to retinoic acid
GO:0009744  response to sucrose stimulus
GO:0007165  signal transduction
GO:0030431  sleep
GO:0035176  social behavior
GO:0042713  sperm ejaculation

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0030141  secretory granule
GO:0043195  terminal button

Molecular Function

GO:0005185  neurohypophyseal hormone activity
GO:0031855  oxytocin receptor binding