oxytocin receptor

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Synonym

OT-R, oxytocin receptor, Oxytocin receptor, OXTR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:5.90

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:237.30

eye:17.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:18.20

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:14.40

GeneChip

cerebrum:4.55

cerebellum:4.40

brain stem:5.37

corpus callosum/glia:4.23

pineal gland:-

peripheral nerve:3.98

spine:4.50

retina:-

eye:-

artery/aorta:4.07

vein:4.97

lymphnode:3.94

peripheral blood:-

spleen:3.88

thymus:4.19

bone marrow:4.29

adipose:3.88

bone:-

skin:4.03

CAGE

cerebrum:0.69

cerebellum:-

brain stem:0.71

corpus callosum/glia:0.07

pineal gland:0.36

peripheral nerve:-

spine:0.92

retina:-

eye:-

artery/aorta:0.79

vein:0

lymphnode:0.03

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.96

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.21

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.05

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:-

prostate:-

ovary:-

testis:26

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:10.60

lung:9.80

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:65.10

salivary:-

GeneChip

uterus:4.27

placenta:3.90

prostate:4.04

ovary:4.77

testis:3.78

heart:4

muscle:3.88

esophagus:3.89

stomach:3.82

intestine:3.94

colon:3.94

liver/hepato:3.74

lung:3.98

bladder:-

kidney:3.83

pituitary:3.99

thyroid/parathyroid:4.02

adrenal gland:4.07

pancreas:3.85

breast:6.75

salivary:4.15

CAGE

uterus:0.45

placenta:0.77

prostate:0.39

ovary:0.95

testis:0.28

heart:0.18

muscle:0

esophagus:0.33

stomach:-

intestine:0.07

colon:0.04

liver/hepato:0

lung:0.36

bladder:0.26

kidney:0.27

pituitary:0.42

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:3.73

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.37

ovary:1.18

testis:0.29

heart:0.13

muscle:0.05

esophagus:-

stomach:-

intestine:-

colon:0.12

liver/hepato:0.02

lung:0.81

bladder:-

kidney:0.34

pituitary:-

thyroid/parathyroid:0.33

adrenal gland:0.19

pancreas:-

breast:3.50

salivary:-

IDs

Refseq ID	NM_000916
Gene ID	5021
Unigene ID	Hs.282067
Probe set ID	206825_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000180914
GTEx ID	ENSG00000180914

Orthologous Gene

Mouse[1]	NM_001081147
Rat [0]

Chromosomal Region

3p25.3 [8,792,094 - 8,811,314]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily
IPR002062	Oxytocin receptor
IPR001817	Vasopressin receptor

Gene Ontology (GO ID)

Biological Process

GO:0007166	cell surface receptor linked signal transduction
GO:0042755	eating behavior
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0070371	ERK1 and ERK2 cascade
GO:0060206	estrous cycle phase
GO:0007565	female pregnancy
GO:0048565	gut development
GO:0007507	heart development
GO:0007595	lactation
GO:0042711	maternal behavior
GO:0060137	maternal process involved in parturition
GO:0007613	memory
GO:0006936	muscle contraction
GO:0060455	negative regulation of gastric acid secretion
GO:0045777	positive regulation of blood pressure
GO:0010701	positive regulation of norepinephrine secretion
GO:0060406	positive regulation of penile erection
GO:0032230	positive regulation of synaptic transmission, GABAergic
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0051965	positive regulation of synaptogenesis
GO:0070474	positive regulation of uterine smooth muscle contraction
GO:0001975	response to amphetamine
GO:0034059	response to anoxia
GO:0042220	response to cocaine
GO:0034097	response to cytokine stimulus
GO:0042493	response to drug
GO:0032355	response to estradiol stimulus
GO:0043434	response to peptide hormone stimulus
GO:0032570	response to progesterone stimulus
GO:0030431	sleep
GO:0035176	social behavior
GO:0042713	sperm ejaculation
GO:0001967	suckling behavior
GO:0021537	telencephalon development

Cellular Component

GO:0016324	apical plasma membrane
GO:0005913	cell-cell adherens junction
GO:0005887	integral to plasma membrane
GO:0005902	microvillus
GO:0005886	plasma membrane

Molecular Function

GO:0004990	oxytocin receptor activity
GO:0017046	peptide hormone binding
GO:0005000	vasopressin receptor activity

oxytocin receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function