platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)

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Synonym

LIS2, PAFAHA, PAFAH alpha, Lissencephaly-1 protein, PAFAH, PAFAH1B1, LIS-1, LIS1, PAF-AH 45 kDa subunit, PAF-AH alpha, PAF acetylhydrolase 45 kDa subunit

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:379.20 cerebellum:415.60 brain stem:- corpus callosum/glia:87.50 pineal gland:296.70 peripheral nerve:184 spine:336.90 retina:118.60 eye:217.40 artery/aorta:119.90 vein:133.30 lymphnode:80.90 peripheral blood:109.30 spleen:113.40 thymus:309.20 bone marrow:78.70 adipose:80.70 bone:76.80 skin:177.60
GeneChip cerebrum:6.67 cerebellum:6.38 brain stem:6.80 corpus callosum/glia:6.80 pineal gland:- peripheral nerve:7.19 spine:6.70 retina:- eye:- artery/aorta:7.39 vein:7.45 lymphnode:7.21 peripheral blood:- spleen:7.03 thymus:7.53 bone marrow:7.38 adipose:7.20 bone:- skin:7.31
CAGE cerebrum:4.77 cerebellum:- brain stem:4.78 corpus callosum/glia:4.44 pineal gland:4.55 peripheral nerve:- spine:4.36 retina:- eye:- artery/aorta:4.03 vein:3.87 lymphnode:3.74 peripheral blood:- spleen:3.81 thymus:4.35 bone marrow:- adipose:3.90 bone:- skin:-
RNA-seq cerebrum:6.23 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:200.50 placenta:116.60 prostate:169 ovary:149.10 testis:203.30 heart:102.20 muscle:40.20 esophagus:- stomach:106.20 intestine:64.80 colon:144.20     liver/hepato:73.90        lung:195.50    bladder:125.60 kidney:93.60 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:102.20 salivary:656.80
GeneChip uterus:6.91 placenta:7.67 prostate:6.69 ovary:6.72 testis:9.93 heart:7.04 muscle:7.11 esophagus:7.66 stomach:6.88 intestine:7.01 colon:6.67 liver/hepato:6.43 lung:7.47 bladder:- kidney:6.76 pituitary:6.58 thyroid/parathyroid:6.93 adrenal gland:6.91 pancreas:6.33 breast:7.13 salivary:6.93
CAGE uterus:4.12 placenta:3.96 prostate:3.93 ovary:4.04 testis:4.39 heart:4.20 muscle:4.82 esophagus:4.06 stomach:- intestine:4.26 colon:3.99     liver/hepato:3.75    lung:4.23 bladder:4.15 kidney:3.91 pituitary:4.36 thyroid/parathyroid:4.02 adrenal gland:- pancreas:3.52 breast:3.52 salivary:3.73
RNA-seq uterus:- placenta:- prostate:4.88 ovary:5.30 testis:5.39 heart:5.02 muscle:5.21 esophagus:- stomach:- intestine:- colon:4.82     liver/hepato:3.48        lung:4.31    bladder:- kidney:4.92 pituitary:- thyroid/parathyroid:5.78 adrenal gland:4.73 pancreas:- breast:4.92 salivary:-

IDs

Refseq ID NM_000430
Gene ID 5048
Unigene ID Hs.77318
Probe set ID 200815_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000007168
GTEx ID ENSG00000007168

Orthologous Gene

Mouse[3]  NM_013625
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0001675  acrosome assembly
GO:0030036  actin cytoskeleton organization
GO:0008344  adult locomotory behavior
GO:0001667  ameboidal cell migration
GO:0048854  brain morphogenesis
GO:0021987  cerebral cortex development
GO:0021895  cerebral cortex neuron differentiation
GO:0021540  corpus callosum morphogenesis
GO:0051660  establishment of centrosome localization
GO:0000132  establishment of mitotic spindle orientation
GO:0000086  G2/M transition of mitotic cell cycle
GO:0021766  hippocampus development
GO:0021819  layer formation in the cerebral cortex
GO:0007611  learning or memory
GO:0016042  lipid catabolic process
GO:0000226  microtubule cytoskeleton organization
GO:0031023  microtubule organizing center organization
GO:0007017  microtubule-based process
GO:0007067  mitosis
GO:0000278  mitotic cell cycle
GO:0046329  negative regulation of JNK cascade
GO:0010977  negative regulation of neuron projection development
GO:0007405  neuroblast proliferation
GO:0050885  neuromuscular process controlling balance
GO:0001764  neuron migration
GO:0051081  nuclear envelope disassembly
GO:0007097  nuclear migration
GO:0046469  platelet activating factor metabolic process
GO:0045773  positive regulation of axon extension
GO:0001961  positive regulation of cytokine-mediated signaling pathway
GO:0045931  positive regulation of mitotic cell cycle
GO:0009306  protein secretion
GO:0032319  regulation of Rho GTPase activity
GO:0008090  retrograde axon cargo transport
GO:0017145  stem cell division
GO:0007268  synaptic transmission
GO:0019226  transmission of nerve impulse
GO:0047496  vesicle transport along microtubule

Cellular Component

GO:0000235  astral microtubule
GO:0005938  cell cortex
GO:0031252  cell leading edge
GO:0043025  cell soma
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030426  growth cone
GO:0005871  kinesin complex
GO:0000776  kinetochore
GO:0005875  microtubule associated complex
GO:0031512  motile primary cilium
GO:0031513  nonmotile primary cilium
GO:0005635  nuclear envelope
GO:0031965  nuclear membrane
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0031982  vesicle

Molecular Function

GO:0034452  dynactin binding
GO:0045502  dynein binding
GO:0045505  dynein intermediate chain binding
GO:0008201  heparin binding
GO:0008017  microtubule binding
GO:0043274  phospholipase binding
GO:0051219  phosphoprotein binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity