peroxiredoxin 1

Synonym

peroxiredoxin 1, PAGA, MSP23, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, Natural killer cell-enhancing factor A, NKEF-A, NKEFA, PRDX1, PAG, TDPX2, PAGB, Proliferation-associated protein PAG, Peroxiredoxin-1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:258.40

cerebellum:37.80

brain stem:-

corpus callosum/glia:204.10

pineal gland:1186.80

peripheral nerve:92

spine:561.50

retina:593.20

eye:446.70

artery/aorta:329.70

vein:866.40

lymphnode:293.20

peripheral blood:200.40

spleen:37.80

thymus:38.70

bone marrow:137.80

adipose:161.30

bone:153.50

skin:417.60

GeneChip

cerebrum:10

cerebellum:9.43

brain stem:10.56

corpus callosum/glia:10.34

pineal gland:-

peripheral nerve:10.40

spine:10.78

retina:-

eye:-

artery/aorta:9.58

vein:9.89

lymphnode:9.66

peripheral blood:-

spleen:8.82

thymus:9.43

bone marrow:8.31

adipose:9.53

bone:-

skin:10.02

CAGE

cerebrum:5.66

cerebellum:-

brain stem:6.08

corpus callosum/glia:5.98

pineal gland:5.98

peripheral nerve:-

spine:6.31

retina:-

eye:-

artery/aorta:5.58

vein:5.04

lymphnode:5.71

peripheral blood:-

spleen:5.51

thymus:4.91

bone marrow:-

adipose:5.49

bone:-

skin:-

RNA-seq

cerebrum:7.29

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.74

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:7.34

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:145.80

placenta:280.50

prostate:292.90

ovary:186.30

testis:56.20

heart:421.50

muscle:904.10

esophagus:-

stomach:191.20

intestine:162

colon:237.40

liver/hepato:760

lung:444.80

bladder:-

kidney:228.70

pituitary:116

thyroid/parathyroid:818.70

adrenal gland:253.90

pancreas:177.80

breast:269.50

salivary:328.40

GeneChip

uterus:9.71

placenta:10

prostate:9.93

ovary:10.02

testis:9.15

heart:9.76

muscle:9.73

esophagus:10.94

stomach:9.34

intestine:9.59

colon:9.47

liver/hepato:9.69

lung:10.10

bladder:-

kidney:10.42

pituitary:9.34

thyroid/parathyroid:10.73

adrenal gland:9.47

pancreas:8.61

breast:9.85

salivary:9.32

CAGE

uterus:5.35

placenta:5.67

prostate:5.32

ovary:5.34

testis:5.08

heart:5.81

muscle:5.62

esophagus:6.21

stomach:-

intestine:6.02

colon:5.40

liver/hepato:5.88

lung:5.76

bladder:5.59

kidney:6.37

pituitary:5.02

thyroid/parathyroid:6.49

adrenal gland:-

pancreas:4.59

breast:5.75

salivary:5.56

RNA-seq

uterus:-

placenta:-

prostate:7.86

ovary:7.72

testis:7.20

heart:6.94

muscle:7.91

esophagus:-

stomach:-

intestine:-

colon:7.46

liver/hepato:8.17

lung:7.94

bladder:-

kidney:8.58

pituitary:-

thyroid/parathyroid:8.97

adrenal gland:8.21

pancreas:-

breast:7.25

salivary:-

IDs

Refseq ID	NM_181697
Gene ID	5052
Unigene ID	Hs.180909
Probe set ID	208680_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000117450
GTEx ID	ENSG00000117450

Orthologous Gene

Mouse[4]	NM_011034
Rat [0]

Chromosomal Region

1p34.1 [45,976,708 - 45,988,719]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0008283	cell proliferation
GO:0034101	erythrocyte homeostasis
GO:0042744	hydrogen peroxide catabolic process
GO:0042267	natural killer cell mediated cytotoxicity
GO:0042345	regulation of NF-kappaB import into nucleus
GO:0032872	regulation of stress-activated MAPK cascade
GO:0019430	removal of superoxide radicals
GO:0001501	skeletal system development

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0042470	melanosome
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion
GO:0005719	nuclear euchromatin
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005782	peroxisomal matrix

Molecular Function

GO:0020037	heme binding
GO:0004601	peroxidase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0008379	thioredoxin peroxidase activity

peroxiredoxin 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function