paired box 3

Synonym

MGC120384, WS1, Paired box protein Pax-3, MGC120381, MGC134778, MGC120382, PAX3, paired box gene 3 (Waardenburg syndrome 1), CDHS, HUP2, MGC120383

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:50.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:110.40

GeneChip

cerebrum:4.77

cerebellum:4.69

brain stem:4.87

corpus callosum/glia:4.67

pineal gland:-

peripheral nerve:4.52

spine:4.63

retina:-

eye:-

artery/aorta:4.49

vein:4.70

lymphnode:4.45

peripheral blood:-

spleen:4.34

thymus:4.27

bone marrow:4.68

adipose:4.60

bone:-

skin:4.76

CAGE

cerebrum:0.46

cerebellum:-

brain stem:1.25

corpus callosum/glia:0.18

pineal gland:3.71

peripheral nerve:-

spine:1.83

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0.84

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.04

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:8.70

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.41

placenta:4.45

prostate:4.36

ovary:4.51

testis:4.61

heart:4.69

muscle:5.05

esophagus:4.59

stomach:4.63

intestine:4.58

colon:4.78

liver/hepato:4.68

lung:4.42

bladder:-

kidney:4.59

pituitary:4.65

thyroid/parathyroid:4.38

adrenal gland:4.56

pancreas:4.47

breast:4.40

salivary:4.69

CAGE

uterus:0.26

placenta:0

prostate:0.08

ovary:0.14

testis:0.04

heart:0.09

muscle:1.30

esophagus:0

stomach:-

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0.12

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.06

ovary:0.00

testis:0.60

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_001127366
Gene ID	5077
Unigene ID	Hs.42146
Probe set ID	216059_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000135903
GTEx ID	ENSG00000135903

Orthologous Gene

Mouse[6]	NM_001159520, NM_008781
Rat [0]

Chromosomal Region

2q36.1 [223,064,607 - 223,163,715]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related
IPR001523	Paired box protein, N-terminal
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0008283	cell proliferation
GO:0007507	heart development
GO:0060594	mammary gland specification
GO:0007517	muscle organ development
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001755	neural crest cell migration
GO:0001843	neural tube closure
GO:0048663	neuron fate commitment
GO:0009887	organ morphogenesis
GO:0048066	pigmentation during development
GO:0008284	positive regulation of cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0007605	sensory perception of sound
GO:0021527	spinal cord association neuron differentiation
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005634

nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

paired box 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function