iroquois homeobox 4

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Synonym

IRXA3, iroquois homeobox protein 4, MGC131996, Iroquois homeobox protein 4, Iroquois-class homeodomain protein IRX-4, Homeodomain protein IRXA3, IRX4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:4.56 cerebellum:4.67 brain stem:4.58 corpus callosum/glia:4.56 pineal gland:- peripheral nerve:4.42 spine:4.40 retina:- eye:- artery/aorta:4.59 vein:4.80 lymphnode:4.47 peripheral blood:- spleen:4.33 thymus:4 bone marrow:4.81 adipose:4.82 bone:- skin:5.66
CAGE cerebrum:0 cerebellum:- brain stem:0.06 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:0.22 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.02 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.33 placenta:4.46 prostate:4.84 ovary:4.31 testis:4.38 heart:5.22 muscle:4.91 esophagus:5.55 stomach:4.39 intestine:4.44 colon:4.67 liver/hepato:4.52 lung:4.30 bladder:- kidney:4.51 pituitary:4.49 thyroid/parathyroid:4.33 adrenal gland:4.46 pancreas:4.98 breast:5.83 salivary:5.28
CAGE uterus:0.16 placenta:0 prostate:1.00 ovary:0 testis:0.32 heart:0.73 muscle:0.13 esophagus:1.17 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0.08 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0.90 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.47 ovary:0.01 testis:0.50 heart:1.53 muscle:0.35 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0.01    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0.06 adrenal gland:0.02 pancreas:- breast:0.63 salivary:-

Gene Information

IDs

Refseq ID NM_016358
Gene ID 50805
Unigene ID Hs.196927
Probe set ID 220225_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000113430
GTEx ID ENSG00000113430

Orthologous Gene

Mouse[1]  NM_018885
Rat[1]  NM_001107330

Chromosomal Region

5p15.33  [1,877,541  -  1,887,350]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

10370142
10625552
11382777
12477932
18497553
19913121
20628086
21544582
21779381
21906983
22323358

Gene Ontology  (GO ID)

Biological Process

GO:0048561  establishment of organ orientation
GO:0007507  heart development

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity