ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

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Synonym

DDEF1, ZG14P, AMAP1, PAG2, ARF GTPase-activating protein 1, PIP2-dependent ARF1 GAP, development and differentiation enhancing factor 1, ASAP1, KIAA1249, Development and differentiation-enhancing factor 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.15 cerebellum:5.18 brain stem:5.98 corpus callosum/glia:5.63 pineal gland:- peripheral nerve:6.27 spine:6.10 retina:- eye:- artery/aorta:5.44 vein:5.18 lymphnode:5.74 peripheral blood:- spleen:6.64 thymus:5.83 bone marrow:6.69 adipose:5.90 bone:- skin:5.51
CAGE cerebrum:2.56 cerebellum:- brain stem:2.74 corpus callosum/glia:2.66 pineal gland:2.10 peripheral nerve:- spine:2.97 retina:- eye:- artery/aorta:3.17 vein:3.26 lymphnode:2.63 peripheral blood:- spleen:3.52 thymus:2.03 bone marrow:- adipose:3.81 bone:- skin:-
RNA-seq cerebrum:3.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.93 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.01 placenta:6.37 prostate:5.65 ovary:5.72 testis:6.33 heart:5.75 muscle:4.97 esophagus:5.15 stomach:5.53 intestine:5.30 colon:4.97 liver/hepato:4.76 lung:5.67 bladder:- kidney:4.97 pituitary:5.56 thyroid/parathyroid:5.02 adrenal gland:5.83 pancreas:4.16 breast:5.41 salivary:4.74
CAGE uterus:3.29 placenta:3.53 prostate:2.69 ovary:3.03 testis:3.83 heart:3.37 muscle:2.58 esophagus:2.70 stomach:- intestine:1.99 colon:2.38     liver/hepato:1.97    lung:3.52 bladder:2.88 kidney:2.20 pituitary:1.77 thyroid/parathyroid:2.29 adrenal gland:- pancreas:1.98 breast:3.40 salivary:1.15
RNA-seq uterus:- placenta:- prostate:3.28 ovary:3.27 testis:4.10 heart:2.63 muscle:1.74 esophagus:- stomach:- intestine:- colon:2.83     liver/hepato:1.56        lung:3.47    bladder:- kidney:2.40 pituitary:- thyroid/parathyroid:2.17 adrenal gland:3.56 pancreas:- breast:3.21 salivary:-

Gene Information

IDs

Refseq ID NM_018482
Gene ID 50807
Unigene ID -
Probe set ID 221039_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000153317
GTEx ID ENSG00000153317

Orthologous Gene

Mouse[2]  NM_010026
Rat [0]  

Chromosomal Region

8q24.21  [131,064,353  -  131,455,906]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

9819391
10574462
11773070
12029088
12058076
12149250
12477932
12522101
12672817
12771146
14702039
15090612
15719014
15897555
16038802
16223492
16344560
16421571
16636290
17255943
17474147
17893324
18094045
18400762
18519696
18685082
19017632
19041431
19322201
19380743
19525955
19531213
20154719
20467438
20697350
20936779
21139048
21352810
21706016
21858086
21988832
22734003
24167568

Gene Ontology  (GO ID)

Biological Process

GO:0060271  cilium morphogenesis
GO:0032312  regulation of ARF GTPase activity

Cellular Component

GO:0005737  cytoplasm
GO:0016020  membrane

Molecular Function

GO:0008060  ARF GTPase activator activity
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0008270  zinc ion binding