pyruvate carboxylase

jump to detail

Synonym

Pyruvic carboxylase, PCB, Pyruvate carboxylase, mitochondrial precursor, pyruvate carboxylase, PC

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:20.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:112.30

retina:-

eye:52.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:59

adipose:80.70

bone:25.60

skin:14.40

GeneChip

cerebrum:6.85

cerebellum:6.74

brain stem:6.95

corpus callosum/glia:6.57

pineal gland:-

peripheral nerve:6.21

spine:7.01

retina:-

eye:-

artery/aorta:6.19

vein:5.61

lymphnode:5.61

peripheral blood:-

spleen:4.97

thymus:5.43

bone marrow:5.68

adipose:7.47

bone:-

skin:6.21

CAGE

cerebrum:3.96

cerebellum:-

brain stem:4.15

corpus callosum/glia:4.02

pineal gland:3.04

peripheral nerve:-

spine:4.08

retina:-

eye:-

artery/aorta:2.56

vein:3.30

lymphnode:2.13

peripheral blood:-

spleen:1.18

thymus:1.84

bone marrow:-

adipose:4.30

bone:-

skin:-

RNA-seq

cerebrum:2.67

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.32

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:22.50

ovary:-

testis:21.60

heart:-

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:17

liver/hepato:21.10

lung:19.60

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.12

placenta:5.43

prostate:5.99

ovary:5.37

testis:6.47

heart:5.58

muscle:5.71

esophagus:5.87

stomach:5.39

intestine:5.49

colon:5.48

liver/hepato:8.29

lung:5.35

bladder:-

kidney:7.18

pituitary:6.10

thyroid/parathyroid:5.70

adrenal gland:6.66

pancreas:6.42

breast:6.17

salivary:7.17

CAGE

uterus:1.85

placenta:2.68

prostate:2.20

ovary:2.18

testis:2.54

heart:2.15

muscle:2.33

esophagus:2.34

stomach:-

intestine:3.28

colon:2.68

liver/hepato:5.75

lung:2.07

bladder:1.84

kidney:3.66

pituitary:2.81

thyroid/parathyroid:2.33

adrenal gland:-

pancreas:2.18

breast:4.24

salivary:4.35

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0.10

testis:0.35

heart:0.50

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:1.39

lung:0

bladder:-

kidney:0.07

pituitary:-

thyroid/parathyroid:0.78

adrenal gland:0.32

pancreas:-

breast:2.41

salivary:-

IDs

Refseq ID	NM_001040716
Gene ID	5091
Unigene ID	Hs.89890
Probe set ID	204476_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000173599
GTEx ID	ENSG00000173599

Orthologous Gene

Mouse[10]	NM_001162946, NM_008797
Rat [0]

Chromosomal Region

11q13.2 [66,615,704 - 66,725,847]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013785	Aldolase-type TIM barrel
IPR011761	ATP-grasp fold
IPR005482	Biotin carboxylase, C-terminal
IPR000891	Pyruvate carboxyltransferase
IPR011054	Rudiment single hybrid motif

GO:0006768	biotin metabolic process
GO:0005975	carbohydrate metabolic process
GO:0006094	gluconeogenesis
GO:0006006	glucose metabolic process
GO:0006629	lipid metabolic process
GO:0006107	oxaloacetate metabolic process
GO:0006090	pyruvate metabolic process
GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process

GO:0005829	cytosol
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion

GO:0005524	ATP binding
GO:0009374	biotin binding
GO:0004075	biotin carboxylase activity
GO:0003677	DNA binding
GO:0046872	metal ion binding
GO:0004736	pyruvate carboxylase activity

pyruvate carboxylase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function