MLX interacting protein-like

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Synonym

Mlx interactor, MLX interacting protein-like, MLX-interacting protein-like, Williams Beuren syndrome chromosome region 14, WS-bHLH, MONDOB, MIO, WBSCR14, CHREBP, WS basic-helix-loop-helix leucine zipper protein, MLXIPL

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.71 cerebellum:7.22 brain stem:6.80 corpus callosum/glia:6.72 pineal gland:- peripheral nerve:6.01 spine:6.42 retina:- eye:- artery/aorta:6.77 vein:6.58 lymphnode:6.29 peripheral blood:- spleen:5.85 thymus:5.75 bone marrow:6.42 adipose:7.42 bone:- skin:6.25
CAGE cerebrum:2.55 cerebellum:- brain stem:1.54 corpus callosum/glia:1.38 pineal gland:3.41 peripheral nerve:- spine:0.64 retina:- eye:- artery/aorta:2.22 vein:2.86 lymphnode:0.60 peripheral blood:- spleen:0.17 thymus:0.23 bone marrow:- adipose:3.58 bone:- skin:-
RNA-seq cerebrum:0.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.44 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.95 placenta:5.93 prostate:5.54 ovary:6.35 testis:6.57 heart:6.76 muscle:7.08 esophagus:6.58 stomach:6.42 intestine:7.03 colon:6.73 liver/hepato:9.51 lung:6.28 bladder:- kidney:7.27 pituitary:6.64 thyroid/parathyroid:6.02 adrenal gland:8.07 pancreas:7.02 breast:6.44 salivary:6.57
CAGE uterus:0.13 placenta:0.08 prostate:0.74 ovary:2.02 testis:2.89 heart:2.10 muscle:3.79 esophagus:1.62 stomach:- intestine:4.32 colon:3.10     liver/hepato:4.56    lung:1.30 bladder:1.47 kidney:3.46 pituitary:2.26 thyroid/parathyroid:1.43 adrenal gland:- pancreas:2.81 breast:3.30 salivary:1.67
RNA-seq uterus:- placenta:- prostate:0.22 ovary:0.00 testis:0.00 heart:0.09 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.16     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.11 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_032953
Gene ID 51085
Unigene ID Hs.647055
Probe set ID 221163_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000009950
GTEx ID ENSG00000009950

Orthologous Gene

Mouse[1]  NM_021455
Rat[1]  NM_021455

Chromosomal Region

7q11.23  [73,007,524  -  73,038,873]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9860302
10780788
11230181
11698644
11724780
12477932
12721358
14702039
14742444
14759258
15163635
15489334
16644671
18193043
18193044
18193046
18591247
18606808
18946681
18950580
19060906
19060911
19148283
19252981
19487539
19571538
19680233
19913121
19995986
20025850
20158509
20167577
20301427
20382893
20570916
20580033
20657596
20679960
20686565
20864672
20965718
20972250
21036147
21145868
21282101
21665952
21726544
21811631
21835137
21840420
21909109
21938000
21988832
22001757
22286219
22338092
22399527
22466288
22546860
23209190
23263486
23443556
23505323
23530060
23597489
23604004
23803610
24097068
24366300
24449882
24616092

Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0006112  energy reserve metabolic process
GO:0055089  fatty acid homeostasis
GO:0042593  glucose homeostasis
GO:0010255  glucose mediated signaling pathway
GO:0071157  negative regulation of cell cycle arrest
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0008284  positive regulation of cell proliferation
GO:0031325  positive regulation of cellular metabolic process
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0045821  positive regulation of glycolysis
GO:0046889  positive regulation of lipid biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0007243  protein kinase cascade
GO:0042304  regulation of fatty acid biosynthetic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent
GO:0070328  triglyceride homeostasis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding