protein-L-isoaspartate (D-aspartate) O-methyltransferase

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Synonym

Protein L-isoaspartyl/D-aspartyl methyltransferase, PCMT1, PIMT, Protein-beta-aspartate methyltransferase, L-isoaspartyl protein carboxyl methyltransferase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:231.10 cerebellum:151.10 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:276 spine:112.30 retina:118.60 eye:129.30 artery/aorta:119.90 vein:66.60 lymphnode:50.60 peripheral blood:72.90 spleen:56.70 thymus:- bone marrow:39.40 adipose:201.70 bone:38.40 skin:96
GeneChip cerebrum:8.58 cerebellum:8.02 brain stem:8.99 corpus callosum/glia:7.57 pineal gland:- peripheral nerve:9.24 spine:8.27 retina:- eye:- artery/aorta:6.71 vein:7.18 lymphnode:6.50 peripheral blood:- spleen:6.61 thymus:7.72 bone marrow:7.97 adipose:7.29 bone:- skin:7.21
CAGE cerebrum:4.76 cerebellum:- brain stem:4.83 corpus callosum/glia:4.30 pineal gland:3.95 peripheral nerve:- spine:4.28 retina:- eye:- artery/aorta:3.71 vein:3.45 lymphnode:3.73 peripheral blood:- spleen:3.70 thymus:4.03 bone marrow:- adipose:4.12 bone:- skin:-
RNA-seq cerebrum:6.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.33 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.29 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:98.40 prostate:90.10 ovary:- testis:108.20 heart:153.30 muscle:140.60 esophagus:- stomach:127.50 intestine:324 colon:42.40     liver/hepato:147.80        lung:88    bladder:- kidney:52 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:102.20 salivary:-
GeneChip uterus:7.42 placenta:6.71 prostate:7.86 ovary:7.31 testis:8.20 heart:7.77 muscle:8.71 esophagus:7.27 stomach:6.82 intestine:7.20 colon:6.84 liver/hepato:6.73 lung:6.66 bladder:- kidney:6.97 pituitary:7.24 thyroid/parathyroid:7.16 adrenal gland:6.46 pancreas:6.69 breast:7.06 salivary:7.27
CAGE uterus:3.83 placenta:3.88 prostate:3.92 ovary:3.77 testis:4.64 heart:4.45 muscle:4.56 esophagus:4.07 stomach:- intestine:3.71 colon:3.65     liver/hepato:4.35    lung:3.79 bladder:3.97 kidney:3.85 pituitary:4.10 thyroid/parathyroid:3.96 adrenal gland:- pancreas:3.47 breast:3.67 salivary:4.25
RNA-seq uterus:- placenta:- prostate:4.60 ovary:4.59 testis:4.77 heart:5.77 muscle:6.06 esophagus:- stomach:- intestine:- colon:4.85     liver/hepato:4.51        lung:4.02    bladder:- kidney:4.10 pituitary:- thyroid/parathyroid:5.53 adrenal gland:3.69 pancreas:- breast:4.98 salivary:-

Gene Information

IDs

Refseq ID NM_005389
Gene ID 5110
Unigene ID Hs.279257
Probe set ID 208857_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120265
GTEx ID ENSG00000120265

Orthologous Gene

Mouse[3]  NM_008786
Rat [0]  

Chromosomal Region

6q25.1  [150,070,579  -  150,132,556]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1339271
1478665
1998518
2684970
3167043
3355545
7592526
8074695
8914929
10343128
10496068
11792715
11847284
11912212
12477932
15489334
16169070
16196087
16256389
17110338
17167531
17207965
17353931
18029348
18381200
18582870
19110265
19161160
19287380
19290383
19738201
19913121
20471030
20628086
20800603
20811636
21081666
21103663
21139048
21145461
21163940
21204776
21319273
21372823
21839816
21841813
21890473
21906983
22033921
22053931
22382029
22412018
22505724
22623428
22647835
22735455
22939629
22990118
23000965
23647599
23903319
24130170
24250222
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006479  protein amino acid methylation
GO:0030091  protein repair

Cellular Component

GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum

Molecular Function

GO:0004719  protein-L-isoaspartate (D-aspartate) O-methyltransferase activity