hydroxysteroid (17-beta) dehydrogenase 11

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Synonym

17betaHSD11, 17-beta-HSD XI, retSDR2, 17-beta-hydroxysteroid dehydrogenase 11, 17-BETA-HSD11, UNQ207/PRO233, 17bHSD11, 17-BETA-HSDXI, RetSDR2, Retinal short-chain dehydrogenase/reductase 2, 17-beta-HSD 11, DHRS8, dehydrogenase/reductase (SDR family) member 8, PAN1B, 17betaHSDXI, HSD17B11, CTCL tumor antigen HD-CL-03, RETSDR2, PSEC0029

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.14 cerebellum:6.81 brain stem:6.59 corpus callosum/glia:6.57 pineal gland:- peripheral nerve:7.13 spine:6.64 retina:- eye:- artery/aorta:7.32 vein:7.02 lymphnode:7.35 peripheral blood:- spleen:7.36 thymus:7.55 bone marrow:8.50 adipose:7.61 bone:- skin:6.58
CAGE cerebrum:3.22 cerebellum:- brain stem:3.46 corpus callosum/glia:3.16 pineal gland:2.11 peripheral nerve:- spine:3.75 retina:- eye:- artery/aorta:3.42 vein:4.12 lymphnode:3.42 peripheral blood:- spleen:3.47 thymus:3.71 bone marrow:- adipose:3.93 bone:- skin:-
RNA-seq cerebrum:4.22 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.61 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:9.30 salivary:-
GeneChip uterus:7.76 placenta:6.92 prostate:7.21 ovary:7.88 testis:5.16 heart:6.82 muscle:5.36 esophagus:5.72 stomach:7.09 intestine:7.83 colon:8.22 liver/hepato:8.72 lung:8.47 bladder:- kidney:7.38 pituitary:6.56 thyroid/parathyroid:6.54 adrenal gland:8.03 pancreas:7.70 breast:6.83 salivary:5.10
CAGE uterus:4.10 placenta:2.96 prostate:3.92 ovary:3.61 testis:3.20 heart:3.04 muscle:2.95 esophagus:3.06 stomach:- intestine:5.48 colon:4.81     liver/hepato:4.61    lung:4.38 bladder:4.17 kidney:3.73 pituitary:3.56 thyroid/parathyroid:3.15 adrenal gland:- pancreas:4.28 breast:4.18 salivary:2.22
RNA-seq uterus:- placenta:- prostate:6.51 ovary:5.03 testis:4.59 heart:3.71 muscle:3.50 esophagus:- stomach:- intestine:- colon:6.49     liver/hepato:6.99        lung:6.09    bladder:- kidney:5.02 pituitary:- thyroid/parathyroid:3.66 adrenal gland:4.91 pancreas:- breast:4.99 salivary:-

Gene Information

IDs

Refseq ID NM_016245
Gene ID 51170
Unigene ID Hs.594923
Probe set ID 217989_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000198189
GTEx ID ENSG00000198189

Orthologous Gene

Mouse[2]  NM_053262
Rat[1]  NM_001004209

Chromosomal Region

4q22.1  [88,257,762  -  88,312,538]

Gene Family (Interpro ID)

IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

9888557
10800688
11165019
12477932
12697717
12975309
14741744
14996095
15489334
16303743
16344560
16712791
18029348
18804447
19027726
19322201
19469652
21139048
21549806
21890473
21906983
22268729
22505724
22797925
23568457

Gene Ontology  (GO ID)

Biological Process

GO:0006710  androgen catabolic process
GO:0006694  steroid biosynthetic process

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005811  lipid particle

Molecular Function

GO:0004303  estradiol 17-beta-dehydrogenase activity
GO:0016229  steroid dehydrogenase activity