dicarbonyl/L-xylulose reductase

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Synonym

XR, DCXR, Carbonyl reductase II, P34H, Kidney dicarbonyl reductase, HCRII, dicarbonyl/L-xylulose reductase, KIDCR, Dicarbonyl/L-xylulose reductase, DCR, Sperm surface protein P34H, kiDCR, L-xylulose reductase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:16.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:30.70 spine:- retina:- eye:135.20 artery/aorta:30 vein:- lymphnode:50.60 peripheral blood:54.70 spleen:18.90 thymus:- bone marrow:- adipose:- bone:25.60 skin:14.40
GeneChip cerebrum:7.69 cerebellum:7.78 brain stem:8.28 corpus callosum/glia:7.22 pineal gland:- peripheral nerve:7.68 spine:7.51 retina:- eye:- artery/aorta:7.43 vein:6.47 lymphnode:7.40 peripheral blood:- spleen:6.91 thymus:7.73 bone marrow:7.21 adipose:8.22 bone:- skin:7.99
CAGE cerebrum:4.16 cerebellum:- brain stem:4.49 corpus callosum/glia:4.15 pineal gland:2.90 peripheral nerve:- spine:3.78 retina:- eye:- artery/aorta:3.11 vein:3.97 lymphnode:3.97 peripheral blood:- spleen:3.59 thymus:3.94 bone marrow:- adipose:4.31 bone:- skin:-
RNA-seq cerebrum:4.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.25 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:61.90 prostate:90.10 ovary:37.30 testis:43.30 heart:51.10 muscle:80.40 esophagus:- stomach:21.20 intestine:- colon:93.30     liver/hepato:211.10        lung:29.30    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:44.50 breast:55.80 salivary:-
GeneChip uterus:6.77 placenta:7.01 prostate:9.29 ovary:7.07 testis:7.94 heart:7.66 muscle:7.89 esophagus:8.07 stomach:7.78 intestine:7.48 colon:7.45 liver/hepato:11.66 lung:7.33 bladder:- kidney:9.98 pituitary:7.89 thyroid/parathyroid:7.89 adrenal gland:7.35 pancreas:7.31 breast:8.03 salivary:8.46
CAGE uterus:3.47 placenta:4.14 prostate:4.35 ovary:4.04 testis:4.27 heart:3.63 muscle:4.91 esophagus:4.40 stomach:- intestine:3.90 colon:4.08     liver/hepato:6.73    lung:4.26 bladder:3.82 kidney:4.66 pituitary:3.60 thyroid/parathyroid:4.64 adrenal gland:- pancreas:4.14 breast:3.93 salivary:4.90
RNA-seq uterus:- placenta:- prostate:5.01 ovary:4.86 testis:5.26 heart:4.24 muscle:5.88 esophagus:- stomach:- intestine:- colon:3.14     liver/hepato:7.88        lung:2.25    bladder:- kidney:5.07 pituitary:- thyroid/parathyroid:5.93 adrenal gland:4.03 pancreas:- breast:5.36 salivary:-

Gene Information

IDs

Refseq ID NM_016286
Gene ID 51181
Unigene ID Hs.9857
Probe set ID 217973_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169738
GTEx ID ENSG00000169738

Orthologous Gene

Mouse[1]  NM_026428
Rat[1]  NM_026428

Chromosomal Region

17q25.3  [79,993,757  -  79,995,573]

Gene Family (Interpro ID)

IPR003560  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

8125298
10385429
11752456
11882650
12136162
12477932
12665801
12680326
15103634
15489334
15906319
16616743
16847567
17434498
17576332
18079483
18086765
19027726
19056867
19337691
19442656
19615732
21139048
21832049
21890473
21906983
21988832
22042873
22505724
23661708
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0042732  D-xylose metabolic process
GO:0006006  glucose metabolic process
GO:0006739  NADP metabolic process
GO:0055114  oxidation reduction
GO:0051289  protein homotetramerization
GO:0005997  xylulose metabolic process

Cellular Component

GO:0005903  brush border
GO:0005881  cytoplasmic microtubule
GO:0016020  membrane
GO:0005902  microvillus

Molecular Function

GO:0050038  L-xylulose reductase (NADP+) activity
GO:0016655  oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor