toll-like receptor 8

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Synonym

MGC119599, MGC119600, toll-like receptor 8, UNQ249/PRO286, Toll-like receptor 8 precursor, TLR8

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:4.04

cerebellum:3.96

brain stem:3.92

corpus callosum/glia:3.79

pineal gland:-

peripheral nerve:4.13

spine:4.15

retina:-

eye:-

artery/aorta:4.18

vein:4.18

lymphnode:4.01

peripheral blood:-

spleen:4.02

thymus:4.19

bone marrow:4.71

adipose:4.19

bone:-

skin:4.22

CAGE

cerebrum:1.08

cerebellum:-

brain stem:1.23

corpus callosum/glia:0.88

pineal gland:0.91

peripheral nerve:-

spine:2.12

retina:-

eye:-

artery/aorta:0.69

vein:1.61

lymphnode:2.90

peripheral blood:-

spleen:4.38

thymus:1.92

bone marrow:-

adipose:2.85

bone:-

skin:-

RNA-seq

cerebrum:0.23

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.35

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.16

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:3.99

placenta:4.36

prostate:3.88

ovary:3.79

testis:4.02

heart:4.37

muscle:4.36

esophagus:4.35

stomach:4.09

intestine:4.11

colon:4.35

liver/hepato:3.98

lung:4.33

bladder:-

kidney:3.95

pituitary:4.09

thyroid/parathyroid:3.92

adrenal gland:3.97

pancreas:4.53

breast:3.93

salivary:4.46

CAGE

uterus:1.05

placenta:2.06

prostate:1.48

ovary:1.29

testis:0.90

heart:1.04

muscle:0.95

esophagus:1.04

stomach:-

intestine:1.39

colon:1.03

liver/hepato:2.03

lung:3.31

bladder:1.42

kidney:1.61

pituitary:0.83

thyroid/parathyroid:1.21

adrenal gland:-

pancreas:0

breast:1.36

salivary:0.83

RNA-seq

uterus:-

placenta:-

prostate:0.42

ovary:0.51

testis:0.31

heart:0.49

muscle:0.22

esophagus:-

stomach:-

intestine:-

colon:0.17

liver/hepato:0.59

lung:1.37

bladder:-

kidney:0.40

pituitary:-

thyroid/parathyroid:0.16

adrenal gland:0.55

pancreas:-

breast:0.95

salivary:-

IDs

Refseq ID	NM_138636
Gene ID	51311
Unigene ID	-
Probe set ID	220832_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000101916
GTEx ID	ENSG00000101916

Orthologous Gene

Mouse[1]	NM_133212
Rat[1]	NM_133212

Chromosomal Region

Xp22.2 [12,924,739 - 12,941,288]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000157

Toll-Interleukin receptor

Gene Ontology (GO ID)

Biological Process

GO:0071260	cellular response to mechanical stimulus
GO:0051607	defense response to virus
GO:0007249	I-kappaB kinase/NF-kappaB cascade
GO:0016064	immunoglobulin mediated immune response
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0045089	positive regulation of innate immune response
GO:0045356	positive regulation of interferon-alpha biosynthetic process
GO:0045359	positive regulation of interferon-beta biosynthetic process
GO:0045078	positive regulation of interferon-gamma biosynthetic process
GO:0045416	positive regulation of interleukin-8 biosynthetic process
GO:0050707	regulation of cytokine secretion
GO:0009615	response to virus
GO:0034158	toll-like receptor 8 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0010008	endosome membrane
GO:0000139	Golgi membrane
GO:0016021	integral to membrane

Molecular Function

GO:0003677	DNA binding
GO:0003725	double-stranded RNA binding
GO:0004872	receptor activity
GO:0003723	RNA binding
GO:0003727	single-stranded RNA binding

toll-like receptor 8

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function