dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

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Synonym

THYEX3, HDPR1, DAPPER1, DACT1, HNG3, Heptacellular carcinoma novel gene 3 protein, hDPR1, FRODO, DAPPER, Dapper homolog 1, DPR1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:4.78 cerebellum:6.75 brain stem:4.55 corpus callosum/glia:4.57 pineal gland:- peripheral nerve:6.65 spine:4.71 retina:- eye:- artery/aorta:6.54 vein:5.88 lymphnode:4.73 peripheral blood:- spleen:5.60 thymus:4.15 bone marrow:4.58 adipose:5.13 bone:- skin:5
CAGE cerebrum:1.61 cerebellum:- brain stem:1.24 corpus callosum/glia:1.04 pineal gland:0.83 peripheral nerve:- spine:1.55 retina:- eye:- artery/aorta:3.15 vein:1.95 lymphnode:0.53 peripheral blood:- spleen:1.52 thymus:0.68 bone marrow:- adipose:1.54 bone:- skin:-
RNA-seq cerebrum:0.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:5.97 placenta:5.57 prostate:6.11 ovary:5.72 testis:6.16 heart:5.11 muscle:4.95 esophagus:4.30 stomach:5.59 intestine:5.16 colon:5.45 liver/hepato:4.37 lung:5.07 bladder:- kidney:4.57 pituitary:4.80 thyroid/parathyroid:6.01 adrenal gland:5.94 pancreas:4.54 breast:4.85 salivary:4.32
CAGE uterus:1.89 placenta:1.59 prostate:2.02 ovary:2.28 testis:1.63 heart:1.67 muscle:0.64 esophagus:1.01 stomach:- intestine:1.39 colon:1.27     liver/hepato:1.12    lung:1.56 bladder:1.99 kidney:0.92 pituitary:0.95 thyroid/parathyroid:2.36 adrenal gland:- pancreas:0 breast:1.92 salivary:0
RNA-seq uterus:- placenta:- prostate:0.04 ovary:0.00 testis:0.00 heart:0.03 muscle:0.22 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.29        lung:0.75    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.60 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001079520
Gene ID 51339
Unigene ID -
Probe set ID 219179_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000165617
GTEx ID ENSG00000165617

Orthologous Gene

Mouse[1]  NM_001190466, NM_021532
Rat[1]  NM_001190466, NM_021532

Chromosomal Region

14q23.1  [59,100,685  -  59,115,039]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
11970895
12508121
12632086
15146197
15580286
16446366
17197390
18029348
18936100
19073771
19733838
20232357
20844743
21176356
21262972
21282530
21382349
21525190
21718540
21900206
22470507
22610794
23073659
23696638

Gene Ontology  (GO ID)

Biological Process

GO:0048813  dendrite morphogenesis
GO:0048619  embryonic hindgut morphogenesis
GO:0001702  gastrulation with mouth forming second
GO:0046329  negative regulation of JNK cascade
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0045600  positive regulation of fat cell differentiation
GO:0045732  positive regulation of protein catabolic process
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0031647  regulation of protein stability
GO:0050808  synapse organization
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0045202  synapse

Molecular Function

GO:0008013  beta-catenin binding
GO:0070097  delta-catenin binding
GO:0005515  protein binding
GO:0051018  protein kinase A binding
GO:0005080  protein kinase C binding