phosphodiesterase 6G, cGMP-specific, rod, gamma

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Synonym

PDE6G, MGC125749, DKFZp686C0587, phosphodiesterase 6G, cGMP-specific, rod, gamma, GMP-PDE gamma, PDEG

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.01 cerebellum:6.17 brain stem:5.94 corpus callosum/glia:5.96 pineal gland:- peripheral nerve:5.84 spine:5.93 retina:- eye:- artery/aorta:6.06 vein:6.30 lymphnode:6.19 peripheral blood:- spleen:6.03 thymus:6.02 bone marrow:6.35 adipose:6.23 bone:- skin:6.18
CAGE cerebrum:0.08 cerebellum:- brain stem:0.21 corpus callosum/glia:0.13 pineal gland:5.48 peripheral nerve:- spine:0.30 retina:- eye:- artery/aorta:0.47 vein:2.31 lymphnode:1.46 peripheral blood:- spleen:2.60 thymus:2.07 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:0.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.97 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.29 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:5.82 placenta:6.55 prostate:5.74 ovary:5.85 testis:6.04 heart:6.05 muscle:6.33 esophagus:5.95 stomach:6 intestine:6.37 colon:6.08 liver/hepato:6.19 lung:5.99 bladder:- kidney:6.07 pituitary:5.98 thyroid/parathyroid:5.77 adrenal gland:5.83 pancreas:6.93 breast:5.75 salivary:6.33
CAGE uterus:0 placenta:1.91 prostate:0.15 ovary:0.37 testis:0.13 heart:0.07 muscle:0.17 esophagus:0.40 stomach:- intestine:0.53 colon:0.12     liver/hepato:0.84    lung:0.85 bladder:0.18 kidney:1.01 pituitary:0 thyroid/parathyroid:0.37 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.13 testis:0.24 heart:0.00 muscle:0.13 esophagus:- stomach:- intestine:- colon:0.15     liver/hepato:0.22        lung:0.80    bladder:- kidney:0.46 pituitary:- thyroid/parathyroid:0.07 adrenal gland:3.10 pancreas:- breast:0.34 salivary:-

Gene Information

IDs

Refseq ID NM_002602
Gene ID 5148
Unigene ID -
Probe set ID 210060_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000185527
GTEx ID ENSG00000185527

Orthologous Gene

Mouse[2]  NM_012065
Rat[2]  NM_012065

Chromosomal Region

17q25.3  [79,617,489  -  79,623,607]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1683837
1965799
2161380
7828894
8125719
8406511
8557689
11076863
11230166
11502744
12107411
12477932
12624098
14502124
15215290
15489334
15489336
16357825
16381901
19798052
20301590
20397626
20655036
20979602

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007596  blood coagulation
GO:0043086  negative regulation of catalytic activity
GO:0007603  phototransduction, visible light
GO:0045742  positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745  positive regulation of G-protein coupled receptor protein signaling pathway
GO:0022400  regulation of rhodopsin mediated signaling pathway
GO:0016056  rhodopsin mediated signaling pathway
GO:0007601  visual perception

Molecular Function

GO:0047555  3',5'-cyclic-GMP phosphodiesterase activity
GO:0030553  cGMP binding
GO:0004857  enzyme inhibitor activity