leucyl-tRNA synthetase

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Synonym

PIG44, LeuRS, KIAA1352, leucyl-tRNA synthetase, hr025Cl, Leucyl-tRNA synthetase, cytoplasmic, LRS, FLJ10595, Leucine--tRNA ligase, LEURS, FLJ21788, LARS, LARS1, LEUS, RNTLS, HSPC192

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:194.40 cerebellum:314.80 brain stem:- corpus callosum/glia:175 pineal gland:- peripheral nerve:184 spine:224.60 retina:- eye:76.40 artery/aorta:179.90 vein:66.60 lymphnode:91 peripheral blood:91.10 spleen:56.70 thymus:116 bone marrow:39.40 adipose:- bone:153.50 skin:139.20
GeneChip cerebrum:8.36 cerebellum:8.56 brain stem:8.15 corpus callosum/glia:8.81 pineal gland:- peripheral nerve:8.55 spine:8.46 retina:- eye:- artery/aorta:8.61 vein:8.05 lymphnode:8.78 peripheral blood:- spleen:8.81 thymus:8.56 bone marrow:8.33 adipose:7.97 bone:- skin:8.58
CAGE cerebrum:4.46 cerebellum:- brain stem:4.57 corpus callosum/glia:4.57 pineal gland:4.90 peripheral nerve:- spine:4.76 retina:- eye:- artery/aorta:4.08 vein:4.18 lymphnode:4.14 peripheral blood:- spleen:4.37 thymus:4.22 bone marrow:- adipose:4.64 bone:- skin:-
RNA-seq cerebrum:4.55 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.18 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.58 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:109.40 placenta:65.60 prostate:33.80 ovary:37.30 testis:173.10 heart:51.10 muscle:80.40 esophagus:- stomach:85 intestine:129.60 colon:178.10     liver/hepato:179.40        lung:298.10    bladder:- kidney:41.60 pituitary:232 thyroid/parathyroid:327.50 adrenal gland:152.40 pancreas:35.60 breast:158 salivary:-
GeneChip uterus:8.63 placenta:7.77 prostate:8.66 ovary:8.65 testis:8.22 heart:8.14 muscle:8.14 esophagus:8.41 stomach:8.60 intestine:8.43 colon:8.36 liver/hepato:8.42 lung:8.74 bladder:- kidney:8.37 pituitary:8.61 thyroid/parathyroid:8.98 adrenal gland:8.89 pancreas:8.40 breast:8.73 salivary:8.13
CAGE uterus:4.60 placenta:3.80 prostate:4.39 ovary:4.62 testis:4.02 heart:4.60 muscle:4.86 esophagus:4.41 stomach:- intestine:4.00 colon:4.13     liver/hepato:3.80    lung:4.18 bladder:4.60 kidney:4.33 pituitary:4.75 thyroid/parathyroid:4.41 adrenal gland:- pancreas:4.29 breast:4.29 salivary:4.98
RNA-seq uterus:- placenta:- prostate:4.57 ovary:5.24 testis:4.66 heart:4.26 muscle:5.68 esophagus:- stomach:- intestine:- colon:4.84     liver/hepato:2.86        lung:3.84    bladder:- kidney:4.34 pituitary:- thyroid/parathyroid:5.08 adrenal gland:4.37 pancreas:- breast:4.48 salivary:-

Gene Information

IDs

Refseq ID NM_020117
Gene ID 51520
Unigene ID Hs.432674
Probe set ID 217810_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000133706
GTEx ID ENSG00000133706

Orthologous Gene

Mouse[1]  NM_134137
Rat[1]  NM_001009637

Chromosomal Region

5q32  [145,492,601  -  145,562,223]

Gene Family (Interpro ID)

IPR004493  Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic

Link to Pubmed  (Pubmed ID)

1651330
6933703
8052601
8078941
8125298
8188258
8449960
9278442
9878398
10200289
10718198
10913161
11042152
11181995
11714285
11829477
12477932
14702039
16055448
16344560
17353931
17363246
17378584
18187620
18446061
18781797
19426743
19702327
19738201
20562859
20805241
21081666
21139048
21145461
21319273
21890473
21906983
21963094
22190034
22424946
22505724
22607940
22623428
22863883
22939629
23000965
23125841
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0006429  leucyl-tRNA aminoacylation
GO:0006418  tRNA aminoacylation for protein translation

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0004823  leucine-tRNA ligase activity
GO:0005515  protein binding