ectonucleotide pyrophosphatase/phosphodiesterase 1

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Synonym

ENPP1, PCA1, PDNP1, M6S1, Phosphodiesterase I/nucleotide pyrophosphatase 1, ectonucleotide pyrophosphatase/phosphodiesterase 1, E-NPP 1, PC1, Ectonucleotide pyrophosphatase/phosphodiesterase 1, Plasma-cell membrane glycoprotein PC-1, NPPS, NPP1, PC-1

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:92 spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:- adipose:40.30 bone:38.40 skin:24
GeneChip cerebrum:4.47 cerebellum:4.27 brain stem:4.94 corpus callosum/glia:4.65 pineal gland:- peripheral nerve:5.75 spine:5.07 retina:- eye:- artery/aorta:6.02 vein:5.58 lymphnode:5.07 peripheral blood:- spleen:4.78 thymus:5.80 bone marrow:4.63 adipose:5.96 bone:- skin:5.21
CAGE cerebrum:0.40 cerebellum:- brain stem:0.96 corpus callosum/glia:1.36 pineal gland:1.49 peripheral nerve:- spine:1.25 retina:- eye:- artery/aorta:3.33 vein:1.53 lymphnode:0.82 peripheral blood:- spleen:1.02 thymus:1.36 bone marrow:- adipose:3.35 bone:- skin:-
RNA-seq cerebrum:0.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.07 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:98.40 prostate:- ovary:37.30 testis:21.60 heart:25.50 muscle:- esophagus:- stomach:63.70 intestine:- colon:25.40     liver/hepato:42.20        lung:19.60    bladder:- kidney:83.20 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:8.90 breast:37.20 salivary:-
GeneChip uterus:6.94 placenta:8.51 prostate:5.93 ovary:6.49 testis:5.19 heart:5.17 muscle:5.38 esophagus:4.82 stomach:5.43 intestine:5.42 colon:5.13 liver/hepato:8.84 lung:5.18 bladder:- kidney:6.06 pituitary:7.21 thyroid/parathyroid:8.78 adrenal gland:5.63 pancreas:6.87 breast:6.45 salivary:5.85
CAGE uterus:3.24 placenta:3.72 prostate:1.89 ovary:2.46 testis:1.94 heart:1.35 muscle:1.56 esophagus:1.34 stomach:- intestine:1.67 colon:1.91     liver/hepato:2.98    lung:1.39 bladder:1.80 kidney:2.83 pituitary:3.87 thyroid/parathyroid:2.99 adrenal gland:- pancreas:2.41 breast:3.87 salivary:2.22
RNA-seq uterus:- placenta:- prostate:1.79 ovary:2.01 testis:2.80 heart:0.80 muscle:0.86 esophagus:- stomach:- intestine:- colon:0.99     liver/hepato:3.22        lung:0.85    bladder:- kidney:2.24 pituitary:- thyroid/parathyroid:3.74 adrenal gland:1.29 pancreas:- breast:3.44 salivary:-

IDs

Refseq ID NM_006208
Gene ID 5167
Unigene ID Hs.527295
Probe set ID 205066_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000197594
GTEx ID ENSG00000197594

Orthologous Gene

Mouse[2]  NM_008813
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0050427  3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0031214  biomineral formation
GO:0046849  bone remodeling
GO:0030643  cellular phosphate ion homeostasis
GO:0032869  cellular response to insulin stimulus
GO:0006091  generation of precursor metabolites and energy
GO:0006955  immune response
GO:0030505  inorganic diphosphate transport
GO:0030308  negative regulation of cell growth
GO:0045599  negative regulation of fat cell differentiation
GO:0046325  negative regulation of glucose import
GO:0045719  negative regulation of glycogen biosynthetic process
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0030279  negative regulation of ossification
GO:0031953  negative regulation of protein amino acid autophosphorylation
GO:0009143  nucleoside triphosphate catabolic process
GO:0006796  phosphate metabolic process
GO:0030500  regulation of bone mineralization
GO:0006771  riboflavin metabolic process
GO:0030730  sequestering of triglyceride
GO:0006766  vitamin metabolic process
GO:0006767  water-soluble vitamin metabolic process

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0050656  3'-phosphoadenosine 5'-phosphosulfate binding
GO:0005524  ATP binding
GO:0005158  insulin receptor binding
GO:0046872  metal ion binding
GO:0003676  nucleic acid binding
GO:0047429  nucleoside-triphosphate diphosphatase activity
GO:0004551  nucleotide diphosphatase activity
GO:0004528  phosphodiesterase I activity
GO:0030247  polysaccharide binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0005044  scavenger receptor activity