ureidopropionase, beta

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Synonym

Beta-ureidopropionase, N-carbamoyl-beta-alanine amidohydrolase, UPB1, ureidopropionase, beta, BUP1, Beta-alanine synthase, BUP-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.70 cerebellum:- brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:4.44 cerebellum:4.36 brain stem:4.52 corpus callosum/glia:4.21 pineal gland:- peripheral nerve:4.21 spine:4.21 retina:- eye:- artery/aorta:4.58 vein:4.41 lymphnode:4.32 peripheral blood:- spleen:4.21 thymus:5.45 bone marrow:4.74 adipose:4.59 bone:- skin:4.76
CAGE cerebrum:0.12 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0.18 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:8.70 heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:116.10        lung:-    bladder:- kidney:218.30 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip uterus:4.28 placenta:4.38 prostate:4.22 ovary:4.26 testis:5.26 heart:4.50 muscle:4.57 esophagus:4.20 stomach:4.37 intestine:4.23 colon:4.16 liver/hepato:9.39 lung:4.50 bladder:- kidney:7.13 pituitary:4.34 thyroid/parathyroid:4.08 adrenal gland:4.35 pancreas:4.29 breast:4.36 salivary:4.21
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.24 heart:0.03 muscle:0 esophagus:0 stomach:- intestine:1.17 colon:0.48     liver/hepato:4.69    lung:0 bladder:0 kidney:2.98 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.10 ovary:0.16 testis:1.88 heart:0.36 muscle:0.09 esophagus:- stomach:- intestine:- colon:0.06     liver/hepato:5.13        lung:0.21    bladder:- kidney:3.13 pituitary:- thyroid/parathyroid:0.13 adrenal gland:0.62 pancreas:- breast:0.09 salivary:-

Gene Information

IDs

Refseq ID NM_016327
Gene ID 51733
Unigene ID Hs.474388
Probe set ID 220507_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100024
GTEx ID ENSG00000100024

Orthologous Gene

Mouse[1]  NM_133995
Rat[1]  NM_133995

Chromosomal Region

22q11.23  [24,863,206  -  24,924,358]

Gene Family (Interpro ID)

IPR003010  Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Link to Pubmed  (Pubmed ID)

3931905
10542323
11508704
12477932
14702039
15385443
15461802
17065070
18075467
18216719
19056867
19913121
20628086
22525402
23238479
24328561

Gene Ontology  (GO ID)

Biological Process

GO:0019483  beta-alanine biosynthetic process
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006206  pyrimidine base metabolic process
GO:0046135  pyrimidine nucleoside catabolic process

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0003837  beta-ureidopropionase activity
GO:0046872  metal ion binding