serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

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Synonym

SERPINF1, PIG35, PEDF, Pigment epithelium-derived factor precursor, Serpin-F1, EPC-1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:106.70

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:2670.20

peripheral nerve:92

spine:-

retina:711.80

eye:599.50

artery/aorta:-

vein:-

lymphnode:30.30

peripheral blood:18.20

spleen:151.30

thymus:38.70

bone marrow:98.40

adipose:443.70

bone:217.50

skin:244.80

GeneChip

cerebrum:6.99

cerebellum:6.42

brain stem:6.02

corpus callosum/glia:6.64

pineal gland:-

peripheral nerve:9.54

spine:6.87

retina:-

eye:-

artery/aorta:9.92

vein:10.55

lymphnode:8.92

peripheral blood:-

spleen:7.55

thymus:8.65

bone marrow:7.04

adipose:10.95

bone:-

skin:9.73

CAGE

cerebrum:2.82

cerebellum:-

brain stem:2.09

corpus callosum/glia:4.97

pineal gland:6.70

peripheral nerve:-

spine:2.54

retina:-

eye:-

artery/aorta:5.13

vein:5.46

lymphnode:4.85

peripheral blood:-

spleen:4.99

thymus:4.30

bone marrow:-

adipose:6.24

bone:-

skin:-

RNA-seq

cerebrum:4.84

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:8.06

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:7.91

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:54.70

placenta:284.20

prostate:101.40

ovary:149.10

testis:212

heart:191.60

muscle:301.40

esophagus:-

stomach:42.50

intestine:-

colon:17

liver/hepato:316.70

lung:107.50

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:168.90

breast:83.60

salivary:-

GeneChip

uterus:10.35

placenta:9.60

prostate:9.32

ovary:10.14

testis:10.82

heart:9.96

muscle:9.94

esophagus:9.05

stomach:8.90

intestine:9.55

colon:8.85

liver/hepato:10.87

lung:8.70

bladder:-

kidney:6.42

pituitary:7.93

thyroid/parathyroid:8.48

adrenal gland:8.18

pancreas:8.71

breast:10.03

salivary:7.72

CAGE

uterus:5.89

placenta:5.36

prostate:5.99

ovary:6.17

testis:6.36

heart:5.80

muscle:5.60

esophagus:5.12

stomach:-

intestine:4.05

colon:4.63

liver/hepato:7.00

lung:4.43

bladder:5.41

kidney:3.76

pituitary:4.22

thyroid/parathyroid:5.18

adrenal gland:-

pancreas:5.83

breast:5.93

salivary:3.75

RNA-seq

uterus:-

placenta:-

prostate:7.37

ovary:7.70

testis:8.03

heart:5.99

muscle:6.76

esophagus:-

stomach:-

intestine:-

colon:7.27

liver/hepato:8.29

lung:6.23

bladder:-

kidney:4.19

pituitary:-

thyroid/parathyroid:6.65

adrenal gland:6.64

pancreas:-

breast:8.39

salivary:-

IDs

Refseq ID	NM_002615
Gene ID	5176
Unigene ID	Hs.532768
Probe set ID	202283_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000132386
GTEx ID	ENSG00000132386

Orthologous Gene

Mouse[2]	NM_011340
Rat[1]	NM_177927

GO:0008283	cell proliferation
GO:0007275	multicellular organismal development
GO:0016525	negative regulation of angiogenesis
GO:0010951	negative regulation of endopeptidase activity
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0050769	positive regulation of neurogenesis
GO:0030162	regulation of proteolysis

GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0042470	melanosome

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function