profilin 1

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Synonym

PFN1, Profilin-1, profilin 1, Profilin I

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:84.10

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:296.70

peripheral nerve:30.70

spine:224.60

retina:-

eye:188.10

artery/aorta:299.80

vein:199.90

lymphnode:626.80

peripheral blood:218.60

spleen:132.30

thymus:77.30

bone marrow:1594.10

adipose:201.70

bone:140.70

skin:288

GeneChip

cerebrum:8.59

cerebellum:8.20

brain stem:8.85

corpus callosum/glia:9.21

pineal gland:-

peripheral nerve:9.68

spine:9.32

retina:-

eye:-

artery/aorta:10.48

vein:10.57

lymphnode:10.91

peripheral blood:-

spleen:10.75

thymus:11.21

bone marrow:11.51

adipose:10.25

bone:-

skin:10.31

CAGE

cerebrum:4.97

cerebellum:-

brain stem:5.33

corpus callosum/glia:5.51

pineal gland:4.54

peripheral nerve:-

spine:5.34

retina:-

eye:-

artery/aorta:6.50

vein:6.72

lymphnode:6.88

peripheral blood:-

spleen:6.90

thymus:7.10

bone marrow:-

adipose:6.20

bone:-

skin:-

RNA-seq

cerebrum:6.89

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:9.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:8.93

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:182.30

placenta:393.40

prostate:45.10

ovary:670.70

testis:43.30

heart:127.70

muscle:140.60

esophagus:-

stomach:403.60

intestine:421.20

colon:627.50

liver/hepato:52.80

lung:161.30

bladder:-

kidney:41.60

pituitary:116

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:293.40

breast:204.40

salivary:328.40

GeneChip

uterus:10.61

placenta:10.13

prostate:10.11

ovary:10.19

testis:8.98

heart:9.35

muscle:7.94

esophagus:10.51

stomach:10.27

intestine:10.16

colon:10.87

liver/hepato:9.85

lung:10.52

bladder:-

kidney:9.91

pituitary:9.04

thyroid/parathyroid:9.82

adrenal gland:9.55

pancreas:9.29

breast:10.54

salivary:9.36

CAGE

uterus:6.12

placenta:6.33

prostate:6.18

ovary:5.98

testis:5.44

heart:5.96

muscle:5.68

esophagus:6.56

stomach:-

intestine:6.52

colon:6.56

liver/hepato:6.74

lung:6.33

bladder:6.58

kidney:6.34

pituitary:4.76

thyroid/parathyroid:5.77

adrenal gland:-

pancreas:5.57

breast:6.18

salivary:5.55

RNA-seq

uterus:-

placenta:-

prostate:9.06

ovary:8.41

testis:8.23

heart:6.69

muscle:7.77

esophagus:-

stomach:-

intestine:-

colon:9.08

liver/hepato:8.34

lung:8.91

bladder:-

kidney:8.36

pituitary:-

thyroid/parathyroid:8.05

adrenal gland:9.65

pancreas:-

breast:8.50

salivary:-

IDs

Refseq ID	NM_005022
Gene ID	5216
Unigene ID	Hs.494691
Probe set ID	200634_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000108518
GTEx ID	ENSG00000108518

Orthologous Gene

Mouse[1]	NM_011072
Rat [0]

Chromosomal Region

17p13.2 [4,848,947 - 4,852,309]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR005454	Profilin, Mammalian
IPR002097	Profilin/allergen

Gene Ontology (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0007596	blood coagulation
GO:0008219	cell death
GO:0071363	cellular response to growth factor stimulus
GO:0001843	neural tube closure
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0051054	positive regulation of DNA metabolic process
GO:0051496	positive regulation of stress fiber formation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050434	positive regulation of viral transcription

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0045202	synapse

Molecular Function

GO:0003779	actin binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0070064	proline-rich region binding
GO:0005515	protein binding
GO:0005102	receptor binding
GO:0017048	Rho GTPase binding

profilin 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function