protein geranylgeranyltransferase type I, beta subunit

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Synonym

Geranylgeranyl transferase type-1 subunit beta, Geranylgeranyl transferase type I subunit beta, GGTI, PGGT1B, GGTase-I-beta, BGGI

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:40.40 peripheral blood:36.40 spleen:- thymus:12.90 bone marrow:- adipose:- bone:12.80 skin:19.20
GeneChip cerebrum:3.02 cerebellum:2.94 brain stem:3.14 corpus callosum/glia:3 pineal gland:- peripheral nerve:2.98 spine:3.15 retina:- eye:- artery/aorta:3.10 vein:3.30 lymphnode:3.07 peripheral blood:- spleen:3.06 thymus:3.20 bone marrow:3.23 adipose:3.11 bone:- skin:3.22
CAGE cerebrum:1.40 cerebellum:- brain stem:1.42 corpus callosum/glia:1.39 pineal gland:1.78 peripheral nerve:- spine:1.51 retina:- eye:- artery/aorta:1.16 vein:1.44 lymphnode:1.86 peripheral blood:- spleen:1.62 thymus:1.47 bone marrow:- adipose:1.44 bone:- skin:-
RNA-seq cerebrum:2.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.48 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:18.20 prostate:11.30 ovary:- testis:8.70 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:24.40    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:27.90 salivary:-
GeneChip uterus:3.18 placenta:3.11 prostate:3.20 ovary:3.07 testis:3.03 heart:3.31 muscle:3.20 esophagus:3.19 stomach:3.06 intestine:3.23 colon:3.34 liver/hepato:3.07 lung:3.05 bladder:- kidney:3.02 pituitary:3.08 thyroid/parathyroid:2.93 adrenal gland:3.08 pancreas:3.33 breast:3 salivary:3.13
CAGE uterus:1.57 placenta:1.20 prostate:1.38 ovary:1.67 testis:1.07 heart:1.61 muscle:1.39 esophagus:1.29 stomach:- intestine:1.56 colon:1.39     liver/hepato:1.37    lung:1.95 bladder:1.18 kidney:1.32 pituitary:1.30 thyroid/parathyroid:1.07 adrenal gland:- pancreas:1.42 breast:1.80 salivary:0.36
RNA-seq uterus:- placenta:- prostate:2.90 ovary:3.09 testis:2.88 heart:2.25 muscle:1.98 esophagus:- stomach:- intestine:- colon:2.53     liver/hepato:2.67        lung:1.53    bladder:- kidney:2.98 pituitary:- thyroid/parathyroid:3.10 adrenal gland:2.99 pancreas:- breast:3.06 salivary:-

Gene Information

IDs

Refseq ID NM_005023
Gene ID 5229
Unigene ID Hs.254006
Probe set ID 206288_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164219
GTEx ID ENSG00000164219

Orthologous Gene

Mouse[1]  NM_172627
Rat [0]  

Chromosomal Region

5q22.3  [114,546,527  -  114,598,569]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1400319
7713879
8106351
11076863
12477932
14598891
15451670
16344560
16893176
19667218
20403997
20446922
21906983
22160308
22632162
22863883
23475391
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0051771  negative regulation of nitric-oxide synthase biosynthetic process
GO:0045787  positive regulation of cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0018344  protein geranylgeranylation
GO:0034097  response to cytokine stimulus

Cellular Component

GO:0005953  CAAX-protein geranylgeranyltransferase complex

Molecular Function

GO:0004662  CAAX-protein geranylgeranyltransferase activity
GO:0046872  metal ion binding