PHD finger protein 1

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Synonym

PHF2, Protein PHF1, PHF1, PHD finger protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:37.90 cerebellum:75.60 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:30.70 spine:112.30 retina:- eye:64.60 artery/aorta:- vein:66.60 lymphnode:121.30 peripheral blood:54.70 spleen:75.60 thymus:103.10 bone marrow:59 adipose:- bone:102.40 skin:24
GeneChip cerebrum:8.49 cerebellum:8.36 brain stem:8.46 corpus callosum/glia:8.42 pineal gland:- peripheral nerve:8.47 spine:8.54 retina:- eye:- artery/aorta:8.88 vein:8.73 lymphnode:8.95 peripheral blood:- spleen:9.13 thymus:8.31 bone marrow:8.10 adipose:8.38 bone:- skin:8.03
CAGE cerebrum:3.46 cerebellum:- brain stem:3.51 corpus callosum/glia:3.25 pineal gland:3.93 peripheral nerve:- spine:3.72 retina:- eye:- artery/aorta:4.06 vein:4.01 lymphnode:3.42 peripheral blood:- spleen:3.41 thymus:2.53 bone marrow:- adipose:3.34 bone:- skin:-
RNA-seq cerebrum:3.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:51 prostate:191.50 ovary:111.80 testis:51.90 heart:25.50 muscle:20.10 esophagus:- stomach:- intestine:32.40 colon:33.90     liver/hepato:10.60        lung:48.90    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:- salivary:-
GeneChip uterus:8.67 placenta:8.51 prostate:8.77 ovary:8.77 testis:9.74 heart:8.59 muscle:7.85 esophagus:8.02 stomach:8.51 intestine:8.42 colon:8.05 liver/hepato:8.29 lung:8.59 bladder:- kidney:8.71 pituitary:9.35 thyroid/parathyroid:9.44 adrenal gland:8.98 pancreas:8.43 breast:8.74 salivary:9.17
CAGE uterus:3.76 placenta:2.93 prostate:3.85 ovary:4.12 testis:3.94 heart:3.72 muscle:3.33 esophagus:3.31 stomach:- intestine:3.14 colon:3.22     liver/hepato:3.16    lung:3.95 bladder:3.98 kidney:3.04 pituitary:4.04 thyroid/parathyroid:3.97 adrenal gland:- pancreas:3.67 breast:4.35 salivary:3.80
RNA-seq uterus:- placenta:- prostate:5.09 ovary:4.79 testis:4.46 heart:3.26 muscle:4.62 esophagus:- stomach:- intestine:- colon:3.16     liver/hepato:1.23        lung:4.87    bladder:- kidney:2.80 pituitary:- thyroid/parathyroid:4.49 adrenal gland:4.16 pancreas:- breast:3.13 salivary:-

Gene Information

IDs

Refseq ID NM_024165
Gene ID 5252
Unigene ID Hs.166204
Probe set ID 40446_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000112511
ENSG00000225553
GTEx ID ENSG00000112511
ENSG00000225553

Orthologous Gene

Mouse[1]  NM_009343
Rat[1]  NM_212538

Chromosomal Region

6p21.32  [33,378,176  -  33,384,230]
HSCHR6_MHC_QBL  [33,306,984  -  33,307,829]
HSCHR6_MHC_SSTO  [33,517,537  -  33,523,618]

Gene Family (Interpro ID)

IPR002999  Tudor domain
IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

8125298
8889548
9545646
11571280
12477932
14574404
15489334
15576338
16189514
16344560
18086877
18285464
18385154
18722875
18976975
19204726
19322201
19851445
20873783
21167174
21890473
22315224
22796436
22918161
23104054
23142980
23150668
23211293
23228662
23879974
23887158
23954330
24285434
24457600
24530230

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0006974  response to DNA damage stimulus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0035098  ESC/E(Z) complex
GO:0005815  microtubule organizing center
GO:0005634  nucleus

Molecular Function

GO:0035064  methylated histone residue binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding